UGCG Antibodies

AND UGCG ELISA kits, UGCG Proteins

Many biological assays use antibodies to detect UGCG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UGCG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UGCG antibodies...

We validate the specificity of these antibodies to UGCG by testing them on tissues known to express UGCG positively and negatively. Browse below to find the UGCG antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UGCG Infographic by Boster Bio

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Anti-Ceramide glucosyltransferase UGCG Antibody

Western blot (WB) analysis of UGCG polyclonal antibody at 1:500 dilution
Lane1:Hela cell lysate
Lane2:Raw264

Human, Mouse, Rat

$405
Cat # A10209
100ul

UGCG Overview

Facts about Ceramide glucosyltransferase.

UGCG 3D structure. Source: alphafold

Ceramide glucosyltransferase (UGCG)

Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also function as"flippase".

Gene Information

Human
Gene Name:	UGCG
Uniprot:	Q16739
Entrez:	7357

Family

Belongs to:

glycosyltransferase 2 family

Alternative Names

ceramide glucosyltransferase; EC 2.4.1.80; GCSGLCT1; GLCT-1; Glucosylceramide synthase; UDP-glucose ceramide glucosyltransferaseUDP-glucose:N-acylsphingosine D-glucosyltransferase

Molecular Weight

Mass (kDA):
44.854 kDA

Genomic Context


Human

Location:	9q31.3
Sequence:	9; NC_000009.12 (111896766..111935369)

Tissue Specificity

Found in all tissues examined.

Subcellular Localizations

Golgi apparatus membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Fatty Liver
Nonalcoholic Fatty Liver Disease
Nerve Degeneration
Neoplasms
Steatohepatitis
Steatosis
Inflammation
Liver Diseases
Insulin Resistance
Nervousness
Obesity

Stomach Neoplasms
Respiratory Papillomatosis
Polyps
Malignant Tumor Of Colon
Sarcoma
Carcinoma
Immunologic Deficiency Syndromes

Pathways

Brain Development
Transport
Gastrulation
Pathogenesis
Glycosylation
Cell Death
Cell Adhesion
Cell Proliferation
Programmed Cell Death
Insulin Secretion
Aging
Neuron Differentiation
Myelination

Cytokinesis
Cartilage Development
Cell Division
Fatty Acid Transport
Coagulation
Cell Cycle
Meiosis

PTMs

Glycosylation

Biotinylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UGCG

References

PMID: 8643456 by Ichikawa S., et al. Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis.

PMID: 1532799 by Jeckel D., et al. Glucosylceramide is synthesized at the cytosolic surface of various Golgi subfractions.