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- Table of Contents
Facts about Uroplakin-1a.
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Human | |
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Gene Name: | UPK1A |
Uniprot: | O00322 |
Entrez: | 11045 |
Belongs to: |
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tetraspanin (TM4SF) family |
TSPAN21; UP1A; UPIA; UPK1A uroplakin 1A; UPK1A; UPKA; Uroplakin Ia
Mass (kDA):
28.879 kDA
Human | |
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Location: | 19q13.12 |
Sequence: | 19; NC_000019.10 (35666516..35678485) |
High expression restricted to ureteric urothelium (most superficial cells); low expression in prostate. Expression in normal urothelial cells is lost in culture. Some expression in tumor cell lines derived from urothelial malignancies.
Membrane; Multi-pass membrane protein.
PMID: 15913809 by Hall G.D., et al. Transcriptional control of the human urothelial-specific gene, uroplakin Ia.
PMID: 9846985 by Lobban E.D., et al. Uroplakin gene expression by normal and neoplastic human urothelium.