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- Table of Contents
USF1 Antibodies
AND USF1 ELISA kits, USF1 Proteins
Many biological assays use antibodies to detect USF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with USF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop USF1 antibodies...
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USF1 Infographic by Boster Bio
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USF1 Overview
Facts about Upstream stimulatory factor 1.
Upstream stimulatory factor 1 (USF1)
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') which is found in many different viral and cellular promoters. .
Gene Information
| Human | |
|---|---|
| Gene Name: | USF1 |
| Uniprot: | P22415 |
| Entrez: | 7391 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BHLHB11; bHLHb11FCHL1; Class B basic helix-loop-helix protein 11; FCHL; HYPLIP1; Major late transcription factor 1; MLTF; MLTFI; UEF; upstream stimulatory factor 1; upstream transcription factor 1; USF
Molecular Weight
Mass (kDA):
33.538 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q23.3 |
| Sequence: | 1; NC_000001.11 (161039251..161045977, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Hyperlipidemia
- Combined Hyperlipidaemia
- Hyperlipidemia, Familial Combined
- Neoplasms
- Diabetes Mellitus
- Liver Carcinoma
- Malignant Neoplasm Of Breast
- Carcinoma
- Lymphohistiocytosis, Hemophagocytic
- Diabetes Mellitus, Non-insulin-dependent
- Obesity
- Immunologic Deficiency Syndromes
Interacting Proteins
- FOSL1
- KAT2B
- TRAF2
Pathways
- Methylation
- Cell Cycle
- Cell Proliferation
- Translation
- Pathogenesis
- Dna Methylation
- Secretion
- Localization
- Rna Interference
- Transport
- Histone Acetylation
- Glucose Homeostasis
- Dna Replication
PTMs
- Phosphorylation
- Methylation
- Acetylation
- Demethylation
- Cleavage
Research Areas
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/USF1
bosterbio.com/bosterbio-gene-info-cards/USF1
References
PMID: 2249772 by Gregor P.D., et al. The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer.
PMID: 14573800 by Rahaus M., et al. Transcription factor USF, expressed during the entire phase of Varicella-zoster virus infection, interacts physically with the major viral transactivator IE62 and plays a significant role in virus replication.