Utrophin Antibodies

AND UTRN ELISA kits, Utrophin Proteins

Many biological assays use antibodies to detect Utrophin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Utrophin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Utrophin antibodies...

We validate the specificity of these antibodies to Utrophin by testing them on tissues known to express UTRN positively and negatively. Browse below to find the UTRN antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Utrophin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the UTRN Western Blot Guide

UTRN Infographic by Boster Bio

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Anti-Utrophin/UTRN Antibody Picoband®

Western blot analysis of Utrophin/UTRN using anti-Utrophin/UTRN antibody (A02194-1)

IF analysis of Utrophin/UTRN using anti-Utrophin/UTRN antibody (A02194-1)

Human, Mouse

ELISA, IF, ICC, WB

$370
Cat # A02194-1
100 μg/vial

UTRN Overview

Facts about Utrophin.

Utrophin (UTRN)

May play a role in anchoring the cytoskeleton to the plasma membrane. .

Gene Information

Human
Gene Name:	UTRN
Uniprot:	P46939
Entrez:	7402

Family

Belongs to:

No superfamily

Alternative Names

DMDLutrophin (homologous to dystrophin); DRP; DRP1DRP-1; Dystrophin-related protein 1; FLJ23678; utrophin

Molecular Weight

Mass (kDA):
394.466 kDA

Genomic Context


Human

Location:	6q24.2
Sequence:	6; NC_000006.12 (144284955..144853034)

Tissue Specificity

Isoform 1 has high expression in muscle. Isoforms Up70 and Up140 were found in all the adult and fetal tissues tested and relatively abundant in lung and kidney.

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Neuromuscular junction.

Diseases

Muscular Dystrophy
Dystrophy
Muscular Dystrophy, Duchenne
Muscular Dystrophy, Animal
Myopathy
Neuromuscular Diseases
Muscular Atrophy
Cardiomyopathies
Fibrosis
Tissue Adhesions
Nervousness
Neoplasms

Proliferative Inflammatory Atrophy
Weakness
Becker Muscular Dystrophy
Wasting Syndrome
Hereditary Diseases
Hypertrophy
Muscle Necrosis

Pathways

Localization
Regeneration
Pathogenesis
Immune Response
Translation
Receptor Clustering
Innervation
Cell Adhesion
Synaptic Transmission
Secretion
Protein Phosphorylation
Muscle Cell Proliferation
Muscle Contraction

Inflammatory Response
Mitochondrial Fusion
Chemotaxis
Mrna Splicing
Cell Differentiation
Organelle Fusion
Testosterone Secretion

PTMs

Phosphorylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UTRN

References

PMID: 1461283 by Tinsley J.M., et al. Primary structure of dystrophin-related protein.

PMID: 10369873 by Wilson J., et al. Up71 and up140, two novel transcripts of utrophin that are homologues of short forms of dystrophin.