Uba1y Antibodies

AND Uba1y ELISA kits, Uba1y Proteins

Many biological assays use antibodies to detect Uba1y, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Uba1y in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Uba1y antibodies...

We validate the specificity of these antibodies to Uba1y by testing them on tissues known to express Uba1y positively and negatively. Browse below to find the Uba1y antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Uba1y Infographic by Boster Bio

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Uba1y Overview

Facts about Ubiquitin-like modifier-activating enzyme 1 Y.

Uba1y 3D structure. Source: alphafold

Ubiquitin-like modifier-activating enzyme 1 Y (Uba1y)

Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and then linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin- E1 thioester and free AMP (By similarity). The Y chromosome form may be involved in the survival and proliferation of differentiating spermatogonia.

Gene Information

Mouse
Gene Name:	Uba1y
Uniprot:	P31254
Entrez:	22202

Family

Belongs to:

ubiquitin-activating E1 family

Alternative Names

Ubiquitin-like modifier-activating enzyme 1 Y

Molecular Weight

Mass (kDA):
118.038 kDA

Genomic Context


Mouse

Location:	Y\|Y A1
Sequence:	Y;

Tissue Specificity

Expressed in testis in A spermatogonia and spermatids but not (or at very low levels) in pachytene spermatocytes. Also expressed in Y-bearing ovaries and at very low levels in adrenal gland.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Uba1y

References

PMID: 10656933 by Levy N., et al. The ubiquitin-activating enzyme E1 homologous genes on the mouse Y Chromosome represent one functional gene and six partial pseudogenes.

PMID: 1684224 by Mitchell M.J., et al. Homology of a candidate spermatogenic gene from the mouse Y chromosome to the ubiquitin-activating enzyme E1.