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- Table of Contents
VAMP2 Antibodies
AND VAMP2 ELISA kits, VAMP2 Proteins
Many biological assays use antibodies to detect VAMP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VAMP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VAMP2 antibodies...
Designing a Western blot for VAMP2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the VAMP2 Western Blot GuideVAMP2 Infographic by Boster Bio
All VAMP2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M02331-1
100 μl
Cat # M02331-1
100 μl
Human, Mouse, Rat
ELISA
$540
Cat # EKC2204
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2204
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1952
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1952
1 kit, containing two 96-well plates and all necessary reagents
VAMP2 Overview
Facts about Vesicle-associated membrane protein 2.
Vesicle-associated membrane protein 2 (VAMP2)
Involved in the targeting and/or fusion of transport vesicles to their target membrane. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | VAMP2 |
| Uniprot: | P63027 |
| Entrez: | 6844 |
Family
| Belongs to: |
|---|
| synaptobrevin family |
Alternative Names
FLJ11460; SYB2; SYB2vesicle-associated membrane protein 2; synaptobrevin 2; synaptobrevin-2; VAMP2; VAMP-2; VAMP-2vesicle associated membrane protein 2; vesicle-associated membrane protein 2 (synaptobrevin 2)
Molecular Weight
Mass (kDA):
12.663 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.1 |
| Sequence: | 17; NC_000017.11 (8159147..8162948, complement) |
Tissue Specificity
Nervous system and skeletal muscle.
Subcellular Localizations
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. Cell membrane. Neuronal synaptic vesicles. Colocalizes with PRKCZ and WDFY2 in intracellular vesicles (PubMed:17313651).
Diseases
- Tetanus
- Diabetes Mellitus
- Nervousness
- Insulin Resistance
- Diabetes Mellitus, Non-insulin-dependent
- Malignant Neoplasms
- Impaired Cognition
- Tissue Adhesions
- Impairment (finding)
- Neurodegenerative Disorders
- Paralysis Flaccid
- Nerve Degeneration
Interacting Proteins
- Picalm
- PRKD3
- SNAP29
- SNCA
- STX1A
- STX4
Pathways
- Exocytosis
- Transport
- Membrane Fusion
- Secretion
- Localization
- Vesicle Fusion
- Endocytosis
- Glucose Transport
- Insulin Secretion
- Synaptic Vesicle Exocytosis
- Synaptic Transmission
- Vesicle Transport
- Vesicle Docking
PTMs
- Cleavage
- Phosphorylation
- Prenylation
- Biotinylation
- Oxidation
- Palmitoylation
Research Areas
- Membrane Vesicle Markers
- Neuronal Cell Markers
- Neuroscience
- Neurotransmission
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VAMP2
bosterbio.com/bosterbio-gene-info-cards/VAMP2
References
PMID: 1976629 by Archer B.T. III, et al. Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2.
PMID: 8760387 by Jagadish M.N., et al. Insulin-responsive tissues contain the core complex protein SNAP-25 (synaptosomal-associated protein 25) A and B isoforms in addition to syntaxin 4 and synaptobrevins 1 and 2.