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Prefoldin subunit 3 Antibodies
AND VBP1 ELISA kits, Prefoldin subunit 3 Proteins
Many biological assays use antibodies to detect Prefoldin subunit 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prefoldin subunit 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prefoldin subunit 3 antibodies...
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VBP1 Infographic by Boster Bio
All VBP1 Products
Product
Figures
Specificity
Applications
Price
Dog, Human, Monkey, Mouse, Rat
IHC, WB
$523
Cat # M08073-1
100 µl
Cat # M08073-1
100 µl
Dog, Human, Monkey, Mouse, Rat
IF, IHC, WB
$523
Cat # M08073-2
100 µl
Cat # M08073-2
100 µl
Human, Mouse
IHC, WB
$523
Cat # M08073
100 µl
Cat # M08073
100 µl
VBP1 Overview
Facts about Prefoldin subunit 3.
Prefoldin subunit 3 (VBP1)
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | VBP1 |
| Uniprot: | P61758 |
| Entrez: | 7411 |
Family
| Belongs to: |
|---|
| prefoldin subunit alpha family |
Alternative Names
HIBBJ46; PFD3; PFDN3VHL-binding protein 1; prefoldin 3; prefoldin subunit 3; VBP-1; VHL binding protein-1; von Hippel-Lindau binding protein 1; Von Hippel-Lindau-binding protein 1
Molecular Weight
Mass (kDA):
22.626 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq28 |
| Sequence: | X; NC_000023.11 (155197007..155239841) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cytoplasm. Nucleus. In complex with VHL can translocate to the nucleus.
Diseases
- Neoplasms
- Von Hippel-lindau Syndrome
- Carcinoma
- Renal Cell Carcinoma
- Malignant Neoplasms
- Kidney Neoplasm
- Conventional (clear Cell) Renal Cell Carcinoma
- Cell Transformation, Neoplastic
- Neoplasm Metastasis
- Hypoxia
- Tumor Angiogenesis
- Pheochromocytoma
Interacting Proteins
- PFDN2
- PFDN4
- PFDN5
- PNMA1
- UBL7
Pathways
- Localization
- Pathogenesis
- Dna Methylation
- Methylation
- Rna Interference
- Translation
- Angiogenesis
- Cell Proliferation
- Dna Hypomethylation
- Oxidative Phosphorylation
- Virulence
- Conjugation
- Mismatch Repair
PTMs
- Phosphorylation
Research Areas
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VBP1
bosterbio.com/bosterbio-gene-info-cards/VBP1
References
PMID: 9339366 by Brinke A., et al. Characterization of the gene (VBP1) and transcript for the von Hippel-Lindau binding protein and isolation of the highly conserved murine homologue.
PMID: 9630229 by Vainberg I.E., et al. Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin.