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- Table of Contents
Facts about Vacuolar protein sorting-associated protein 29.
The recruitment of the CSC into the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes into the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for freight protein recycling.
Human | |
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Gene Name: | VPS29 |
Uniprot: | Q9UBQ0 |
Entrez: | 51699 |
Belongs to: |
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VPS29 family |
DC15; DC7; DKFZp564F0223; EC 3.1.3.3; FLJ20492; hVPS29; PEP11 homolog; PEP11; retromer protein; vacuolar protein sorting 29 (yeast homolog); vacuolar protein sorting 29 (yeast); vacuolar protein sorting 29 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 29; vacuolar sorting protein VPS29/PEP11; Vesicle protein sorting 29; x 007 protein
Mass (kDA):
20.506 kDA
Human | |
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Location: | 12q24.11 |
Sequence: | 12; NC_000012.12 (110491083..110502140, complement) |
Ubiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes, thymus, colon skeletal muscle, kidney and brain.
Cytoplasm. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Early endosome. Late endosome.
PMID: 11062004 by Edgar A.J., et al. Human homologues of yeast vacuolar protein sorting 29 and 35.
PMID: 11102511 by Renfrew Haft C., et al. Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes.