WASH complex subunit 3 Antibodies

AND WASHC3 ELISA kits, WASH complex subunit 3 Proteins

Many biological assays use antibodies to detect WASH complex subunit 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WASH complex subunit 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WASH complex subunit 3 antibodies...

We validate the specificity of these antibodies to WASH complex subunit 3 by testing them on tissues known to express WASHC3 positively and negatively. Browse below to find the WASHC3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WASHC3 Infographic by Boster Bio

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CCDC53 (WASHC3) (NM_016053) Human Over-expression Lysate

Human

$628
Cat # LS051019
20 µg, 100 µg

WASHC3 Overview

Facts about WASH complex subunit 3.

WASH complex subunit 3 (WASHC3)

Acts at least in part as part of the WASH core complex whose assembly in the surface of endosomes appears to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates through endosome sorting (PubMed:19922875, PubMed:20498093). .

Gene Information

Human
Gene Name:	WASHC3
Uniprot:	Q9Y3C0
Entrez:	51019

Family

Belongs to:

CCDC53 family

Alternative Names

WASH complex subunit 3

Molecular Weight

Mass (kDA):
21.173 kDA

Genomic Context


Human

Location:	12q23.2
Sequence:	12; NC_000012.12 (102012840..102062124, complement)

Subcellular Localizations

Early endosome.

Interacting Proteins

BLOC1S6
CCDC197
CEP55
COG6
DTNBP1

GOLGA2
HAUS1
HSBP1
IFT20
KDM1A

KNSTRN
MCRS1
MOB1B
NDC80
NUP62

OPTN
PBXIP1
PCM1
SDCBP
SYCE1

TXLNA
TXLNB

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WASHC3

References

PMID: 19922875 by Derivery E., et al. The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.

PMID: 20498093 by Jia D., et al. WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes.