WBP11 Antibodies

AND WBP11 ELISA kits, WBP11 Proteins

Many biological assays use antibodies to detect WBP11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WBP11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WBP11 antibodies...

We validate the specificity of these antibodies to WBP11 by testing them on tissues known to express WBP11 positively and negatively. Browse below to find the WBP11 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WBP11 Infographic by Boster Bio

All WBP11 Products

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Anti-WBP11 Antibody

Human, Mouse, Rat

ELISA, IP, IHC, WB

$370
Cat # A09396-1
100 μl/vial

WBP11 Overview

Facts about WW domain-binding protein 11.

WBP11 3D structure. Source: alphafold

WW domain-binding protein 11 (WBP11)

Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity.

Gene Information

Human
Gene Name:	WBP11
Uniprot:	Q9Y2W2
Entrez:	51729

Family

Belongs to:

No superfamily

Alternative Names

DKFZp779M1063; Npw38-binding protein NpwBP; Npw38-binding protein; NpwBP; NPWBPsplicing factor, PQBP1 and PP1 interacting; SH3 domain-binding protein SNP70; SIPP1WW domain-binding protein 11; SNP70; Splicing factor that interacts with PQBP-1 and PP1; WBP-11; WW domain binding protein 11

Molecular Weight

Mass (kDA):
69.998 kDA

Genomic Context


Human

Location:	12p12.3
Sequence:	12; NC_000012.12 (14784582..14803478, complement)

Subcellular Localizations

Nucleus. Cytoplasm. Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin.

Diseases

Neurodegenerative Disorders
Leukoencephalopathy, Progressive Multifocal
Ataxia
Ataxia, Spinocerebellar

Interacting Proteins

C5orf22
FYN
GRB2
MCRS1
PCBP1

PPP1CA
PQBP1
TESC
TRAF4

Pathways

Localization
Mrna Splicing
Interphase
Pathogenesis
Nuclear Export
Nuclear Import

PTMs

Phosphorylation

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WBP11

References

PMID: 10593949 by Komuro A., et al. Association of two nuclear proteins, Npw38 and NpwBP, via the interaction between the WW domain and a novel proline-rich motif containing glycine and arginine.

PMID: 11375989 by Craggs G., et al. A nuclear SH3 domain-binding protein that colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks.