WDPCP Antibodies

AND WDPCP ELISA kits, WDPCP Proteins

Many biological assays use antibodies to detect WDPCP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WDPCP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WDPCP antibodies...

We validate the specificity of these antibodies to WDPCP by testing them on tissues known to express WDPCP positively and negatively. Browse below to find the WDPCP antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WDPCP Infographic by Boster Bio

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WDPCP (NM_001042692) Human Over-expression Lysate

WDPCP Human Over-expression Lysates NM_001042692

Human

$628
Cat # LS051057
20 µg, 100 µg

WDPCP Overview

Facts about WD repeat-containing and planar cell polarity effector protein fritz homolog.

WDPCP 3D structure. Source: alphafold

WD repeat-containing and planar cell polarity effector protein fritz homolog (WDPCP)

Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core part of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity).

Gene Information

Human
Gene Name:	WDPCP
Uniprot:	O95876
Entrez:	51057

Family

Belongs to:

WD repeat fritz family

Alternative Names

WD repeat-containing and planar cell polarity effector protein fritz homolog

Molecular Weight

Mass (kDA):
85.084 kDA

Genomic Context


Human

Location:	2p15
Sequence:	2; NC_000002.12 (63119559..63588733, complement)

Subcellular Localizations

Cell membrane. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WDPCP

References

PMID: 20671153 by Kim S.K., et al. Planar cell polarity acts through septins to control collective cell movement and ciliogenesis.

PMID: 25427950 by Saari J., et al. Compound heterozygosity for a frame shift mutation and a likely pathogenic sequence variant in the planar cell polarity-ciliogenesis gene WDPCP in a girl with polysyndactyly, coarctation of the aorta, and tongue hamartomas.