Wipi1 Antibodies

AND Wipi1 ELISA kits, Wipi1 Proteins

Many biological assays use antibodies to detect Wipi1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Wipi1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Wipi1 antibodies...

We validate the specificity of these antibodies to Wipi1 by testing them on tissues known to express Wipi1 positively and negatively. Browse below to find the Wipi1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Wipi1 Infographic by Boster Bio

All Wipi1 Products

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Specificity

Applications

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Anti-WIPI1 Antibody

Western blot analysis of WIPI1 in rat colon tissue lysate with WIPI1 antibody at (A) 1 and (B) 2 μg/mL

Immunofluorescence of WIPI1 in human colon tissue with WIPI1 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, WB

$481
Cat # A06206
0.1 mg

Anti-WIPI1 Antibody

Western blot analysis of extracts of various cell lines, using WIPI1 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A06206-1
100ul

Anti-WIPI1 Mouse Monoclonal Antibody [Clone ID: OTI10F4]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY WIPI1 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 2 different cell lines by using anti-WIPI1 monoclonal antibody (1:500)

Human, Mouse, Rat

$523
Cat # M06206
100 µl

Anti-WIPI1 Mouse Monoclonal Antibody [Clone ID: OTI11B11]

Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-WIPI1 mouse monoclonal antibody

Human, Mouse, Rat

IHC, WB

$523
Cat # M06206-1
100 µl

Anti-WIPI1 Rabbit Monoclonal Antibody

Western blot analysis of WIPI1 using anti-WIPI1 antibody (M06206-2)

IHC analysis of WIPI1 using anti-WIPI1 antibody (M06206-2)

Human, Mouse, Rat

IHC, WB

$370
Cat # M06206-2
100 μl/vial

WIPI1 (NM_017983) Human Over-expression Lysate

Human

$628
Cat # LS055062
20 µg, 100 µg

Wipi1 Overview

Facts about WD repeat domain phosphoinositide-interacting protein 1.

WD repeat domain phosphoinositide-interacting protein 1 (Wipi1)

Plays an important role in autophagy and specifically starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions upstream of the ATG12-ATG5-ATG16L1 complex and LC3, and downstream of the ULK1 and PI3-kinase complexes.

Involved in xenophagy of Staphylococcus aureus. Invading S.

Gene Information

Mouse
Gene Name:	Wipi1
Uniprot:	Q8R3E3
Entrez:	52639

Family

Belongs to:

WD repeat SVP1 family

Alternative Names

Atg18 protein homolog; Atg18; ATG18A; FLJ10055; WD repeat domain phosphoinositide-interacting protein 1; WD repeat domain, phosphoinositide interacting 1; WD40 repeat protein interacting with phosphoinositides of 49 kDa; WD40 repeat protein Interacting with phosphoInositides of 49kDa; WIPI 49 kDa; WIPI-1 alpha; WIPI-1; WIPI49ATG18

Molecular Weight

Mass (kDA):
48.758 kDA

Genomic Context


Mouse

Location:	11 E1\|11 72.18 cM
Sequence:	11;

Diseases

Malignant Neoplasms
Hereditary Diseases
Microphthalmos
Nerve Degeneration
Hypoxia
Malignant Paraganglionic Neoplasm
Autoimmune Diseases
Foot-and-mouth Disease
Cardiovascular Diseases
Metabolic Diseases
Corneal Diseases
Neoplasms
Conjunctival Diseases

Blepharitis
Genetic Diseases, Inborn
Malignant Neoplasm Of Ovary
Epithelial Ovarian Cancer
Ovarian Neoplasm
Tuberculosis
Dry Eye Syndromes

Pathways

Autophagy
Macroautophagy
Cell Migration
Cytokine Production
Cellular Homeostasis
Response To Hypoxia
Tear Secretion

Secretion

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Wipi1

References

PMID: 21896713 by Pfisterer S.G., et al. Ca2+/calmodulin-dependent kinase (CaMK) signaling via CaMKI and AMP- activated protein kinase contributes to the regulation of WIPI-1 at the onset of autophagy.

PMID: 22275429 by Itakura E., et al. Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy.