WWP1 Antibodies

AND WWP1 ELISA kits, WWP1 Proteins

Many biological assays use antibodies to detect WWP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WWP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WWP1 antibodies...

We validate the specificity of these antibodies to WWP1 by testing them on tissues known to express WWP1 positively and negatively. Browse below to find the WWP1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WWP1 Infographic by Boster Bio

All WWP1 Products

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WWP1 (NM_007013) Human Over-expression Lysate

Human

$628
Cat # LS011059
20 µg, 100 µg

WWP1 Overview

Facts about NEDD4-like E3 ubiquitin-protein ligase WWP1.

WWP1 3D structure. Source: alphafold

NEDD4-like E3 ubiquitin-protein ligase WWP1 (WWP1)

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and boosts their proteasomal degradation.

Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7.

Gene Information

Human
Gene Name:	WWP1
Uniprot:	Q9H0M0
Entrez:	11059

Family

Belongs to:

No superfamily

Alternative Names

AIP5; AIP5Nedd-4-like ubiquitin-protein ligase; atrophin-1 interacting protein 5; Atrophin-1-interacting protein 5; DKFZP434D2111; EC 6.3.2; EC 6.3.2.-; HSDRP1; NEDD4-like E3 ubiquitin-protein ligase WWP1; TGIF-interacting ubiquitin ligase 1; TIUL1; Tiul11; WW domain containing E3 ubiquitin protein ligase 1; WW domain-containing protein 1; WWP1

Molecular Weight

Mass (kDA):
105.202 kDA

Genomic Context


Human

Location:	8q21.3
Sequence:	8; NC_000008.11 (86342547..86468503)

Tissue Specificity

Detected in heart, placenta, pancreas, kidney, liver, skeletal muscle, bone marrow, fetal brain, and at much lower levels in adult brain and lung. Isoform 1 and isoform 5 predominate in all tissues tested, except in testis and bone marrow, where isoform 5 is expressed at much higher levels than isoform 1.