Xaa-Pro aminopeptidase 1 Antibodies

AND XPNPEP1 ELISA kits, Xaa-Pro aminopeptidase 1 Proteins

Many biological assays use antibodies to detect Xaa-Pro aminopeptidase 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Xaa-Pro aminopeptidase 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Xaa-Pro aminopeptidase 1 antibodies...

We validate the specificity of these antibodies to Xaa-Pro aminopeptidase 1 by testing them on tissues known to express XPNPEP1 positively and negatively. Browse below to find the XPNPEP1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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XPNPEP1 Infographic by Boster Bio

All XPNPEP1 Products

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Anti-XPP1 XPNPEP1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A09499
100ul

XPNPEP1 (NM_020383) Human Recombinant Protein

Coomassie blue staining of purified XPNPEP1 protein

$1249
Cat # PROTQ9NQW7
20 µg

Anti-XPNPEP1 Mouse Monoclonal Antibody [Clone ID: OTI1E3]

HEK293T cells were transfected with pCMV6-ENTRY XPNPEP1 or the pCMV6-ENTRY control (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-XPNPEP1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human) (1:200)

Immunohistochemical staining of paraffin-embedded Human thyroid tissue within the normal limits using anti-XPNPEP1 mouse monoclonal antibody

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M09499
100 µl

XPNPEP1 (NM_020383) Human Over-expression Lysate

XPNPEP1 Human Over-expression Lysates NM_001167604

Human

$628
Cat # LS007511
20 µg, 100 µg

XPNPEP1 Overview

Facts about Xaa-Pro aminopeptidase 1.

XPNPEP1 3D structure. Source: alphafold

Xaa-Pro aminopeptidase 1 (XPNPEP1)

Contributes to the degradation of bradykinin.
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, for example Arg-Pro-Pro.

Gene Information

Human
Gene Name:	XPNPEP1
Uniprot:	Q9NQW7
Entrez:	7511

Family

Belongs to:

peptidase M24B family

Alternative Names

Aminoacylproline aminopeptidase; Aminopeptidase P1; APP1; Cytosolic aminopeptidase P; cytosolic; EC 3.4.11.9; SAMP; xaa-Pro aminopeptidase 1; XPNPEP1; XPNPEPLX-prolyl aminopeptidase (aminopeptidase P)-like; X-prolyl aminopeptidase (aminopeptidase P) 1, soluble; X-prolyl aminopeptidase 1, soluble

Molecular Weight

Mass (kDA):
69.918 kDA

Genomic Context


Human

Location:	10q25.1
Sequence:	10; NC_000010.11 (109864766..109923553, complement)

Tissue Specificity

Expressed in all tissues tested, including pancreas, heart, muscle, kidney, liver, lung and brain. Highest levels in pancreas.

Subcellular Localizations

Cytoplasm.

Diseases

Atresia
Biliary Atresia
Microcephaly
Cns Disorder
Coughing
Infarction
Developmental Delay (disorder)
Nervous System Disorder
Growth Retardation
Hypertensive Disease
Fibrosis
Myocardial Infarction

Metabolic Diseases
Nervousness
Kidney Diseases
Hepatic Fibrosis
Liver Cirrhosis
Persistent Cough

Pathways

Flight
Brain Development
Immune Response
Pathogenesis
Excretion

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/XPNPEP1

References

PMID: 9465902 by Vanhoof G., et al. Isolation and sequence analysis of a human cDNA clone (XPNPEPL) homologous to X-prolyl aminopeptidase (aminopeptidase P).

PMID: 10871044 by Sprinkle T.J., et al. Cloning, chromosomal sublocalization of the human soluble aminopeptidase P gene (XPNPEP1) to 10q25.3 and conservation of the putative proton shuttle and metal ligand binding sites with XPNPEP2.