ZBTB14 Antibodies

AND ZBTB14 ELISA kits, ZBTB14 Proteins

Many biological assays use antibodies to detect ZBTB14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZBTB14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZBTB14 antibodies...

We validate the specificity of these antibodies to ZBTB14 by testing them on tissues known to express ZBTB14 positively and negatively. Browse below to find the ZBTB14 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZBTB14 Infographic by Boster Bio

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ZBTB14 Overview

Facts about Zinc finger and BTB domain-containing protein 14.

ZBTB14 3D structure. Source: alphafold

Zinc finger and BTB domain-containing protein 14 (ZBTB14)

Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'- CCTGCACAGTTCACGGA-3'. Binds to 5'-d(GCC)(n)-3' trinucleotide repeats in promoter regions and acts as a repressor of the FMR1 gene.

Transcriptional repressor of MYC and thymidine kinase promoters. .

Gene Information

Human
Gene Name:	ZBTB14
Uniprot:	O43829
Entrez:	7541

Family

Belongs to:

krueppel C2H2-type zinc-finger protein family

Alternative Names

Nothing Found

Molecular Weight

Mass (kDA):
50.956 kDA

Genomic Context


Human

Location:	18p11.31
Sequence:	18; NC_000018.10 (5289019..5297053, complement)

Subcellular Localizations

Nucleus. Colocalizes with ZBTB21 in nucleus in HEK293 cells.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Immunologic Deficiency Syndromes
Neoplasms
Mammary Neoplasms
Severe Myopia
Congenital Abnormality
Myopia
Autoimmune Reaction
Fragile X Syndrome
Hiv Infections
Dermatomyositis

Scleroderma
Hypoxia
Dysostoses
Carcinoma
Anoxia
Cell Transformation, Neoplastic
Primary Neoplasm

Interacting Proteins

AP1M1
ATP5PO
BYSL
CBX8
CDK16

CDKL3
CEP19
EAF1
EIF1AD
ENKD1

EPM2AIP1
FAM161A
FAM90A1
GORASP2
INTS3

KAT5
MAD2L1BP
MFAP1
MORF4L2
NAA10

PIN1
PNKP
POLR2L
RPL9
RPS7

SCNM1
SDCBP
SNRPB2
SYT16
TCEANC

TXN2
ZCCHC10
ZMAT2

Pathways

Translation
Localization
Rna Interference
Transport
Dna Methylation
Endocytosis
Spermatogenesis
Nuclear Transport
Methylation
Reverse Transcription
Coagulation
Cell Death
Cell Cycle

Histone Acetylation
Cell Growth
Rna Processing
Pathogenesis
Glycolysis
Meiosis
Oncogenesis

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZBTB14

References

PMID: 9244432 by Sobek-Klocke I., et al. The human gene ZFP161 on 18p11.21-pter encodes a putative c-myc repressor and is homologous to murine Zfp161 (Chr 17) and Zfp161-rs1 (X Chr).

PMID: 9177479 by Sugiura K., et al. Expression cloning and intracellular localization of a human ZF5 homologue.