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- Table of Contents

Facts about Zinc fingers and homeoboxes protein 2.
May play a role in retinal development where it modulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (By similarity). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (By similarity).
| Human | |
|---|---|
| Gene Name: | ZHX2 |
| Uniprot: | Q9Y6X8 |
| Entrez: | 22882 |

| Belongs to: |
|---|
| ZHX family |

zona pellucida glycoprotein 2 (sperm receptor); Zona pellucida glycoprotein 2; zona pellucida glycoprotein ZP2; Zona pellucida protein A; zona pellucida sperm-binding protein 2; Zp-2; ZPA
Mass (kDA):
92.307 kDA

| Human | |
|---|---|
| Location: | 8q24.13 |
| Sequence: | 8; NC_000008.11 (122781655..122974514) |
Ubiquitously expressed. Expressed in podocytes.
Nucleus. Colocalizes with EFNB1 intracellular domain in the nucleus.





PMID: 12741956 by Kawata H., et al. Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor.
PMID: 14659886 by Kawata H., et al. The mouse zinc-fingers and homeoboxes (ZHX) family: ZHX2 forms a heterodimer with ZHX3.