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- Table of Contents

Facts about Zinc finger protein 143.
Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8.
| Human | |
|---|---|
| Gene Name: | ZNF143 |
| Uniprot: | P52747 |
| Entrez: | 7702 |

| Belongs to: |
|---|
| GLI C2H2-type zinc-finger protein family |

hStaf; pHZ-1; SBF; SBFzinc finger protein 143 (clone pHZ-1); Selenocysteine tRNA gene transcription-activating factor; SPH-binding factor; STAF; STAFpHZ-1; transcriptional activator Staf; zinc finger protein 143; ZNF143
Mass (kDA):
68.896 kDA

| Human | |
|---|---|
| Location: | 11p15.4 |
| Sequence: | 11; NC_000011.10 (9460965..9528524) |
Expressed in all tissues tested, with the strongest expression in ovary.
Nucleus.




PMID: 7557990 by Tommerup N., et al. Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders.
PMID: 9776743 by Rincon J.C., et al. Molecular cloning of a cDNA encoding human SPH-binding factor, a conserved protein that binds to the enhancer-like region of the U6 small nuclear RNA gene promoter.