Zinc finger protein 658 Antibodies

AND ZNF658 ELISA kits, Zinc finger protein 658 Proteins

Many biological assays use antibodies to detect Zinc finger protein 658, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc finger protein 658 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc finger protein 658 antibodies...

We validate the specificity of these antibodies to Zinc finger protein 658 by testing them on tissues known to express ZNF658 positively and negatively. Browse below to find the ZNF658 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ZNF658 Overview

Facts about Zinc finger protein 658.

ZNF658 3D structure. Source: alphafold

Zinc finger protein 658 (ZNF658)

Mediates transcriptional repression in response to zinc. Represses several genes, such as SLC30A5, SLC30A10 and CBWD1, by binding to the zinc transcriptional regulatory element (ZTRE) (5'- C[AC]C[TAG]CC[TC]-N(0-50)-[GA]G[ATC]G[TG]G-3') found in the promoter region.

May play a role in the control of ribosome biogenesis, regulating predominantly rRNA levels, in addition to those of several ribosomal proteins, thus coordinating this highly zinc- requiring procedure with all the available zinc supply. .

Gene Information

Human
Gene Name:	ZNF658
Uniprot:	Q5TYW1
Entrez:	26149

Family

Belongs to:

krueppel C2H2-type zinc-finger protein family

Alternative Names

Zinc finger protein 658

Molecular Weight

Mass (kDA):
122.274 kDA

Genomic Context


Human

Location:	9q21.11
Sequence:	9; NC_000009.12 (66900725..66932141)

Subcellular Localizations

Nucleus.

PTMs

Isopeptide bond

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZNF658

References

PMID: 25582195 by Ogo O.A., et al. The zinc finger protein ZNF658 regulates the transcription of genes involved in zinc homeostasis and affects ribosome biogenesis through the zinc transcriptional regulatory element.