Kinesin-like protein KIF7 Antibodies

AND Kif7 ELISA kits, Kinesin-like protein KIF7 Proteins

Many biological assays use antibodies to detect Kinesin-like protein KIF7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Kinesin-like protein KIF7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Kinesin-like protein KIF7 antibodies...

We validate the specificity of these antibodies to Kinesin-like protein KIF7 by testing them on tissues known to express Kif7 positively and negatively. Browse below to find the Kif7 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Kif7 Infographic by Boster Bio

All Kif7 Products

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Applications

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Anti-Kif 7 Monoclonal Antibody

13 Q&As

Immunohistochemical analysis of paraffin-embedded human spleen tissue

Immunofluorescence analysis of Hela cell

Human, Mouse, Rat

IF, IHC

$399
Cat # A04321
100μl

Anti-Zebrafish KIF7 Antibody

Zebrafish

$470
Cat # DZ04321
200 μl/vial

Anti-zebrafish KIF7 Antibody

Zebrafish

$470
Cat # DZ04321-1
200 μl/vial

Anti-KIF7 Antibody Picoband®

Western blot analysis of KIF7 using anti-KIF7 antibody (A04321-3)

Human

$370
Cat # A04321-3
100 μg/vial

KIF7 (NM_198525) Human Over-expression Lysate

Human

$960
Cat # LS374654
20 µg, 100 µg

Kif7 Overview

Facts about Kinesin-like protein KIF7.

Kinesin-like protein KIF7 (Kif7)

Essential for hedgehog signaling regulation: acts as both a positive and negative regulator of sonic hedgehog (Shh) and Indian hedgehog (Ihh) pathways, acting downstream of SMO, through both SUFU-dependent and -independent mechanisms. Involved in the regulation of microtubular dynamics.

Required for proper organization of the ciliary suggestion and control of ciliary localization of SUFU-GLI2 complexes. Required for localization of GLI3 to cilia in response to Shh.

Gene Information

Mouse
Gene Name:	Kif7
Uniprot:	B7ZNG0
Entrez:	16576

Family

Belongs to:

TRAFAC class myosin-kinesin ATPase superfamily

Alternative Names

EQYK340; kinesin family member 7; kinesin-like protein KIF7; MGC120653; MGC138476; MGC138478; UNQ340

Molecular Weight

Mass (kDA):
151.624 kDA

Genomic Context


Mouse

Location:	7\|7 D2
Sequence:	7;

Tissue Specificity

Expressed in heart, lung, liver, kidney, testis, spleen and cerebellum.

Diseases

Malignant Neoplasms
Neoplasms
Acrocallosal Syndrome
Malignant Neoplasm Of Pancreas
Cell Transformation, Neoplastic
Malignant Neoplasm Of Stomach
Carcinogenesis
Carcinoma
Basal Cell Carcinoma
Colorectal Cancer
Stomach Neoplasms
Familial Aplasia Of The Vermis

Dysplasia
Congenital Absence
Congenital Abnormality
Polydactyly
Hypoplasia
Inflammation
Melanoma

Pathways

Localization
Cell Proliferation
Proteolysis
Regeneration
Tissue Homeostasis
Transport
Hair Follicle Development
Aging
Stem Cell Maintenance
Skin Development
Intracellular Signal Transduction
Endocytosis

Chondrocyte Proliferation
Cell Fate Specification
Tissue Regeneration
Chondrocyte Development
Cell Cycle
Intraflagellar Transport
Rna Interference

PTMs

Phosphorylation
Cleavage

Acetylation
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Kif7

References

PMID: 19592253 by Endoh-Yamagami S., et al. The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.

PMID: 19666503 by Liem K.F. Jr., et al. Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling.