IGFBP-5 Insulin-Like Growth Factor Binding Protein-5 Human Recombinant Protein

IGFBP-5 protein, Human

IGFBP5 Human Recombinant produced in E. coli is non-glycosylated homodimer containing 2x252 amino acids and having a molecular mass of 28.6kDa. IGFBP5 is purified by proprietary chromatographic techniques.

Product Info Summary

SKU: PROTP24593
Size: 5ug, 25ug, 1mg
Origin Species: Human
Source: Escherichia coli

Product Name

IGFBP-5 Insulin-Like Growth Factor Binding Protein-5 Human Recombinant Protein

View all IGFBP-5 recombinant proteins

SKU/Catalog Number

PROTP24593

Size

5ug, 25ug, 1mg

Description

IGFBP5 Human Recombinant produced in E. coli is non-glycosylated homodimer containing 2x252 amino acids and having a molecular mass of 28.6kDa. IGFBP5 is purified by proprietary chromatographic techniques.

Storage & Handling

Lyophilized IBP5 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IGFBP 5 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Cite This Product

IGFBP-5 Insulin-Like Growth Factor Binding Protein-5 Human Recombinant Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP24593)

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

IBP-5 was lyophilized from a concentrated (1mg/ml) solution containing 10mM sodium Citrate pH-3.

Purity

Greater than 96.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

Predicted MW

30.57kDa

Reconstitution

It is recommended to reconstitute the lyophilized Insulin-Like Growth Factor Binding Protein-5 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Amino Acid Sequence

LGSFVHCEPC DEKALSMCPP SPLGCELVKE PGCGCCMTCA LAEGQSCGVY TERCAQGLRC LPRQDEEKPL HALLHGRGVC LNEKSYREQV KIERDSREHE EPTTSEMAEE TYSPKIFRPK HTRISELKAE AVKKDRRKKL TQSKFVGGAE NTAHPRIISA PEMRQESEQG PCRRHMEASL QELKASPRMV PRAVYLPNCD RKGFYKRKQC KPSRGRKRGI CWCVDKYGMK LPGMEYVDGD FQCHTFDSSN VE

Biological Activity

The ED50, calculated by its ability to inhibit IGF-II induced proliferation of MCF-7. The expected ED50 for this effect is less than 0.4µg/ml, corresponding to a specific activity of greater than 2500 IU/mg in the presence of 15ng/ml of rHuIGF-II.

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Reconstitution

It is recommended to reconstitute the lyophilized Insulin-Like Growth Factor Binding Protein-5 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Validation Images & Assay Conditions

Gene/Protein Information For IGFBP5 (Source: Uniprot.org, NCBI)

Gene Name

IGFBP5

Full Name

Insulin-like growth factor-binding protein 5

Weight

30.57kDa

Alternative Names

IBP5IBP-5; IGF-binding protein 5; IGFBP5; IGFBP-5; insulin-like growth factor binding protein 5; insulin-like growth factor-binding protein 5 IGFBP5 IBP5 insulin like growth factor binding protein 5 insulin-like growth factor-binding protein 5|IBP-5|IGF-binding protein 5|IGFBP-5

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

For more info on IGFBP5, check out the IGFBP5 Infographic

IGFBP5 infographic

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In this infographic, you will see the following information for IGFBP5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].

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SKU:PROTP24593

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