Anti-ABCB5 Monoclonal Antibody

Product Name

Anti-ABCB5 Monoclonal Antibody

View all Abcb5 Antibodies

SKU/Catalog Number

M02979

Size

100ul

Form

Liquid

Description

Boster Bio Anti-ABCB5 Monoclonal Antibody catalog # M02979. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ABCB5 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02979)

Host

Mouse

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Monoclonal

Clone Number

11A2

Isotype

IgG

Immunogen

Synthetic Peptide

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

M02979 is reactive to Abcb5 in Human

Applications

M02979 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

137.397kDa

Background of Abcb5

Anti-Procalcitonin antibody detects human Procalcitonin. Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, a N terminal residue, calcitonin and katacalcin. Levels of unprocessed procalcitonin rise significantly after bacterial infection, trauma or shock. This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:2000

Validation Images & Assay Conditions

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Figure 2. Immunohistochemistry validation of ABCB5 using Anti-ABCB5 Monoclonal Antibody (M02979).

Immunohistochemical analysis of human-breast-cancer tissue. Anti-ABCB5 at 1:200 (4°C

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Figure 3. Immunohistochemistry validation of ABCB5 using Anti-ABCB5 Monoclonal Antibody (M02979).

Immunohistochemical analysis of human kidney tissue. Anti-ABCB5 at 1:200 (4°C

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Figure 4. Immunohistochemistry validation of ABCB5 using Anti-ABCB5 Monoclonal Antibody (M02979).

Immunohistochemical analysis of human liver cancer tissue. Anti-ABCB5 at 1:200 (4°C

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Figure 5. Immunohistochemistry validation of ABCB5 using Anti-ABCB5 Monoclonal Antibody (M02979).

Immunohistochemical analysis of human liver tissue. Anti-ABCB5 at 1:200 (4°C

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Figure 6. Immunohistochemistry validation of ABCB5 using Anti-ABCB5 Monoclonal Antibody (M02979).

Immunohistochemical analysis of human lung cancer tissue. Anti-ABCB5 at 1:200 (4°C

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Figure 1. Western blotting validation for Anti-ABCB5 Monoclonal Antibody M02979

Western blot (WB) analysis of ABCB5 monoclonal antibody.
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration

Gene/Protein Information For Abcb5 (Source: Uniprot.org, NCBI)

Alternative Names

ABCB5 P-gp; ABCB5; ABCB5alpha; ABCB5beta; ATP-binding cassette protein; ATP-binding cassette sub-family B member 5; ATP-binding cassette, sub-family B (MDR/TAP), member 5; EC 3.6.3; EC 3.6.3.44; EST422562; P-glycoprotein ABCB5 Abcb5|9230106F14Rik|ATP-binding cassette, sub-family B (MDR/TAP), member 5|ATP-binding cassette sub-family B member 5|ABCB5 P-gp|P-glycoprotein ABCB5

For more info on Abcb5, check out the Abcb5 Infographic

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In this infographic, you will see the following information for Abcb5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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