Product Info Summary
SKU: | M03481 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Mouse |
Application: | Flow Cytometry, WB |
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Product info
Product Name
Anti-AGPS Purified Monoclonal Antibody
SKU/Catalog Number
M03481
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-AGPS Purified Monoclonal Antibody (Catalog# M03481). Tested in Flow Cytometry, WB application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-AGPS Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03481)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
AGPS-03
Isotype
Mouse IgG2a
Immunogen
Recombinant human AGPS (amino acids 158-384). The mouse monoclonal antibody AGPS-03 recognizes AGPS (alkykglycerone phosphate synthase), an intracellular peroxisomal enzyme important for lipid biosynthesis.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M03481 is reactive to AGPS in Human
Applications
M03481 is guaranteed for Flow Cytometry, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
72.912kDa
Background of AGPS
AGPS (alkylglycerone phosphate synthase), is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 μg/ml. Intracellular staining.
Western blotting: 1-2 μg/ml.
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-AGPS Purified Monoclonal Antibody M03481
Western blotting analysis of AGPS in HEK293 cell lysate using monoclonal antibody AGPS-03.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For AGPS (Source: Uniprot.org, NCBI)
Gene Name
AGPS
Full Name
Alkyldihydroxyacetonephosphate synthase, peroxisomal
Weight
72.912kDa
Superfamily
FAD-binding oxidoreductase/transferase type 4 family
Alternative Names
ADAP-S; ADAS; ADHAPSAlkylglycerone-phosphate synthase; ADPS; Aging-associated gene 5 protein; aging-associated protein 5; ALDHPSY; Alkyl-DHAP synthase; alkyldihydroxyacetonephosphate synthase, peroxisomal; alkylglycerone phosphate synthase; DKFZp762O2215; EC 2.5.1.26; FLJ99755 AGPS ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY, RCDP3 alkylglycerone phosphate synthase alkyldihydroxyacetonephosphate synthase, peroxisomal|aging-associated gene 5 protein|aging-associated protein 5|alkyl-DHAP synthase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on AGPS, check out the AGPS Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for AGPS: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-AGPS Purified Monoclonal Antibody (M03481)
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No publications found for M03481
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