Anti-Akirin-1 Akirin1 Antibody

Akirin1 antibody

Boster Bio Anti-Akirin-1 Akirin1 Antibody (Catalog # A12102). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A12102
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, WB

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Product Name

Anti-Akirin-1 Akirin1 Antibody

View all Akirin1 Antibodies

SKU/Catalog Number

A12102

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Akirin-1 Akirin1 Antibody (Catalog # A12102). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Akirin1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Akirin-1 Akirin1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12102)

Host

Rabbit

Contents

Akirin1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Akirin1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of the human Akirin1. The immunogen is located within the first 50 amino acids of Akirin1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12102 is reactive to Akirin1 in Human, Mouse, Rat

Applications

A12102 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

21.676kDa

Background of Akirin1

The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-κB-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-κB pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-α and IL-1β signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Akirin1 antibody can be used for detection of Akirin1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For Akirin1 (Source: Uniprot.org, NCBI)

Gene Name

Akirin1

Full Name

Akirin-1

Weight

21.676kDa

Superfamily

akirin family

Alternative Names

AKIRIN1 akirin 1; C1orf108; RP11-781D11.2; STRF2 Akirin1|6330407G11Rik|akirin 1|akirin-1|mighty protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Akirin1, check out the Akirin1 Infographic

Akirin1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Akirin1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Size

Total: $449

SKU:A12102

Backordered.

Lead time for this item is typically 4-7 days

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A12102
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$449.00

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