Product Info Summary
SKU: | A03802 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-Aldh5A1 Antibody
SKU/Catalog Number
A03802
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Aldh5A1 Antibody (Catalog # A03802). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Aldh5A1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Aldh5A1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03802)
Host
Rabbit
Contents
Aldh5A1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Aldh5A1 antibody was raised against a 22 amino acid synthetic peptide near the carboxy terminus of the human Aldh5A1. The immunogen is located within the last 50 amino acids of Aldh5A1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03802 is reactive to ALDH5A1 in Human, Mouse, Rat
Applications
A03802 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
57.215kDa
Background of ALDH5A1
Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Aldh5A1 antibody can be used for detection of Aldh5A1 by Western blot at 0.25 - 0.5 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of Aldh5A1 in human liver tissue lysate with Aldh5A1 antibody at (A) 0.25 and (B) 0.5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ALDH5A1 (Source: Uniprot.org, NCBI)
Gene Name
ALDH5A1
Full Name
Succinate-semialdehyde dehydrogenase, mitochondrial
Weight
57.215kDa
Superfamily
aldehyde dehydrogenase family
Alternative Names
aldehyde dehydrogenase 5 family, member A1; EC 1.2.1; EC 1.2.1.24; NAD(+)-dependent succinic semialdehyde dehydrogenase; SSADHmitochondrial ALDH5A1 SSADH, SSDH aldehyde dehydrogenase 5 family member A1 succinate-semialdehyde dehydrogenase, mitochondrial|NAD(+)-dependent succinic semialdehyde dehydrogenase|mitochondrial succinate semialdehyde dehydrogenase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ALDH5A1, check out the ALDH5A1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ALDH5A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Aldh5A1 Antibody (A03802)
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No publications found for A03802
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