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Product Info Summary
| SKU: | A05894 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-Alpha-2,8-sialyltransferase 8B ST8SIA2 Antibody
View all ST8 alpha-2,8-Sialyltransferase 8B/ST8SIA2 Antibodies
SKU/Catalog Number
A05894
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Alpha-2,8-sialyltransferase 8B ST8SIA2 Antibody catalog # A05894. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Alpha-2,8-sialyltransferase 8B ST8SIA2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05894)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human BMP-5.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05894 is reactive to ST8SIA2 in Human, Mouse, Rat
Applications
A05894 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
42.43kDa
Background of ST8 alpha-2,8-Sialyltransferase 8B/ST8SIA2
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
Chen D., Gene 174:129-134(1996) [PubMed: 8863739].
Bao X.,Eur. J. Biochem. 269:259-271(2002) [PubMed: 11784320].
Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].<
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC 1:50-1:200
Validation Images & Assay Conditions
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Figure 2. Immunohistochemistry validation of ST8SIA2 using Anti-Alpha-2
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Figure 3. Immunohistochemistry validation of ST8SIA2 using Anti-Alpha-2
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Figure 1. Western blotting validation for Anti-Alpha-2
Protein Target Info & Infographic
Gene/Protein Information For ST8SIA2 (Source: Uniprot.org, NCBI)
Gene Name
ST8SIA2
Full Name
Alpha-2,8-sialyltransferase 8B
Weight
42.43kDa
Superfamily
glycosyltransferase 29 family
Alternative Names
alpha-2,8-sialyltransferase 8B 1; alpha-2,8-sialyltransferase 8B; EC 2.4.99; EC 2.4.99.-; HsT19690; MGC116854; MGC116857; sialyltransferase 8 (alpha-2, 8-sialytransferase) B; Sialyltransferase 8B; Sialyltransferase X; Sialytransferase St8Sia II; SIAT8B; SIAT8-B; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; ST8SIA2; ST8SiaII; ST8SIA-II; STX; STXST8SiaII ST8SIA2 HsT19690, SIAT8-B, SIAT8B, ST8SIA-II, ST8SiaII, STX ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 alpha-2,8-sialyltransferase 8B|ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 2|alpha-2,8-sialyltransferase 8B 1|sialyltransferase 8 (alpha-2, 8-sialytransferase) B|sialyltransferase 8B|sialyltransferase St8Sia II|sialyltransferase X
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ST8SIA2, check out the ST8SIA2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ST8SIA2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Alpha-2,8-sialyltransferase 8B ST8SIA2 Antibody (A05894)
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