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- Table of Contents
CDC23 antibody (A05798-1) performs well in ELISA, ICC, WB and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
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Immunocytochemistry of APC8 in K562 cells with APC8 antibody at 5 μg/mL.
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Anti-APC8 CDC23 Antibody
CDC23 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Rabbit | ELISA, ICC, WB |
Recommend Dilution
Application
Dilution
Species
APC8 antibody can be used for detection of APC8 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-APC8 CDC23 Antibody
View all CDC23 Antibodies
View all CDC23 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
APC8 antibody can be stored at 4°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Host
Rabbit
Contents
APC8 Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
APC8 antibody was raised against a 17 amino acid synthetic peptide near the center of human APC8. The immunogen is located within amino acids 270 - 320 of APC8.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
68.8 kDa
Background of CDC23
Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC8 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. In Drosophila, silencing of APC8 results in developmental delay and pupal lethality with elevated levels of apoptosis, high mitotic index, and delayed or blocked mitosis.
Cite This Product
Anti-APC8 CDC23 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05798-1)
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Product Promise
We promise Anti-APC8 CDC23 Antibody performs excellently in relevant applications for ELISA, ICC, WB. If it doesn't perform as promised, we will refund the product. Learn more
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A05798-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
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Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 5, 2026