Anti-APEH Antibody

Product Name

Anti-APEH Antibody

View all APEH Antibodies

SKU/Catalog Number

A08394

Size

100ul

Form

Liquid

Description

Boster Bio Anti-APEH Antibody catalog # A08394. Tested in WB,IP applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-APEH Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08394)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human WNT8A protein.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A08394 is reactive to APEH in Human, Mouse, Rat

Applications

A08394 is guaranteed for IP, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

81.225kDa

Background of APEH

This gene (PTENP1) is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
IP: 1:20-1:50

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For APEH (Source: Uniprot.org, NCBI)

Alternative Names

AARE; ACPH; acylamino-acid-releasing enzyme; acylaminoacyl-peptidase; Acyl-peptide hydrolase; APH; D3F15S2; D3S48EEC 3.4.19.1; DNF15S2; MGC2178; N-acylaminoacyl-peptide hydrolase; OPH; Oxidized protein hydrolase APEH AARE, ACPH, APH, D3F15S2, D3S48E, DNF15S2, OPH acylaminoacyl-peptide hydrolase acylamino-acid-releasing enzyme|N-acylaminoacyl-peptide hydrolase|acyl-peptide hydrolase|acylaminoacyl-peptidase|oxidized protein hydrolase

For more info on APEH, check out the APEH Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for APEH: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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