Click image to see more details
Product Info Summary
| SKU: | A01088 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-APOBEC3B Antibody
SKU/Catalog Number
A01088
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-APOBEC3B Antibody (Catalog # A01088). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
APOBEC3B antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-APOBEC3B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01088)
Host
Rabbit
Contents
APOBEC3B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
APOBEC3B antibody was raised against a 14 amino acid peptide near the amino terminus of human APOBEC3B. The immunogen is located within amino acids 20 - 70 of APOBEC3B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
APOBEC3B antibody is human, mouse and rat reactive . At least three isoforms of APOBEC3B are known to exist; this antibody will detect all three. APOBEC3B antibody may cross-react with APOBEC3D.
Reactive Species
A01088 is reactive to APOBEC3B in Human
Applications
A01088 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
45.924kDa
Background of APOBEC3B
The Apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like (APOBEC) 3 is a multi-isoform member of the cytosine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates (1). Similar to TRIM5? which targets incoming retroviral capsids, APOBEC3 plays a major role in cellular defense against retroviral infection (2,3). APOBEC3B has also been shown to be upregulated in several cancers; it is thought that APOBEC3B-catalyzed genomic uracil lesions are responsible for a large proportion of mutations in multiple distinct cancers (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
APOBEC3B antibody can be used for detection of APOBEC3B by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of APOBEC3B in HepG2 cell lysate with APOBEC3B antibody at 1 μg/ml.
Click image to see more details
Immunohistochemistry of APOBEC3B in human small intestine tissue with APOBEC3B antibody at 5 μg/mL.
Click image to see more details
Immunofluorescence of APOBEC3B in human small intestine tissue with APOBEC3B antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For APOBEC3B (Source: Uniprot.org, NCBI)
Gene Name
APOBEC3B
Full Name
DNA dC->dU-editing enzyme APOBEC-3B
Weight
45.924kDa
Superfamily
cytidine and deoxycytidylate deaminase family
Alternative Names
APOBEC1L; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B; ARCD3; ARP4; bK150C2.2; cytidine deaminase; DJ742C19.2; EC 3.5.4; EC 3.5.4.-; FLJ21201; phorbolin 3; Phorbolin-1-related protein; phorbolin-2/3; PHRBNLphorbolin 2; probable DNA dC->dU-editing enzyme APOBEC-3B APOBEC3B A3B, APOBEC1L, ARCD3, ARP4, DJ742C19.2, PHRBNL, bK150C2.2 apolipoprotein B mRNA editing enzyme catalytic subunit 3B DNA dC->dU-editing enzyme APOBEC-3B|apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B|cytidine deaminase|phorbolin 2|phorbolin 3|phorbolin-1-related protein|phorbolin-2/3|probable DNA dC->dU-editing enzyme APOBEC-3B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on APOBEC3B, check out the APOBEC3B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for APOBEC3B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-APOBEC3B Antibody (A01088)
Hello CJ!
No publications found for A01088
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-APOBEC3B Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-APOBEC3B Antibody
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
