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Product Info Summary
| SKU: | A08491 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-APOBEC3D/APOBEC3F Antibody
SKU/Catalog Number
A08491
Size
100ul
Form
Liquid
Description
Boster Bio Anti-APOBEC3D/APOBEC3F Antibody catalog # A08491. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-APOBEC3D/APOBEC3F Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08491)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human RGL2 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A08491 is reactive to APOBEC3D in Human, Mouse, Rat
Applications
A08491 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
46.598kDa
Background of APOBEC3D
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.
Loftus B.J., Genomics 60:295-308(1999).
Wang Y., J. Immunol. 169:1102-1109(2002).
Pang T., J. Biol. Chem. 277:43771-43777(2002).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For APOBEC3D (Source: Uniprot.org, NCBI)
Gene Name
APOBEC3D
Full Name
DNA dC->dU-editing enzyme APOBEC-3D
Weight
46.598kDa
Superfamily
cytidine and deoxycytidylate deaminase family
Alternative Names
APOBEC3DE; APOBEC3E; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D (putative); apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3E pseudogene; ARP6; DNA dC->dU-editing enzyme APOBEC-3D; EC 3.5.4; EC 3.5.4.-; probable DNA dC->dU-editing enzyme APOBEC-3D APOBEC3D A3D, A3DEE, APOBEC3E, ARP6, APOBEC3D apolipoprotein B mRNA editing enzyme catalytic subunit 3D DNA dC->dU-editing enzyme APOBEC-3D|apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D|apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3E pseudogene|probable DNA dC->dU-editing enzyme APOBEC-3D
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on APOBEC3D, check out the APOBEC3D Infographic
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In this infographic, you will see the following information for APOBEC3D: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-APOBEC3D/APOBEC3F Antibody (A08491)
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No publications found for A08491
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