Anti-ARHGEF11/Pdz Rhogef Antibody

Product Name

Anti-ARHGEF11/Pdz Rhogef Antibody

View all ARHGEF11 Antibodies

SKU/Catalog Number

A04614

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-ARHGEF11/Pdz Rhogef Antibody (Catalog # A04614). Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ARHGEF11/Pdz Rhogef Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04614)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from N-terminal of human ARHGEF11.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04614 is reactive to ARHGEF11 in Human

Reconstitution

Observed Molecular Weight

Calculated molecular weight

167704 MW

Background of ARHGEF11

May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.

Nagase T., DNA Res. 4:141-150(1997).
Gregory S.G., Nature 441:315-321(2006).
Ruemenapp U., FEBS Lett. 459:313-318(1999).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A04614 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Positive Control

Validation Images & Assay Conditions

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Western blot analysis of extracts from A549 cells and COLO 205 cells, using ARHGEF11 antibody A04614.

Gene/Protein Information For ARHGEF11 (Source: Uniprot.org, NCBI)

Alternative Names

DKFZp667F1223; glutamate transporter EAAT4-associated protein 48; GTRAP48; KIAA0380rho guanine nucleotide exchange factor 11; PDZ-RHOGEF; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; RhoA-specific guanine nucleotide exchange factor; RhoGEF glutamate transport modulator ARHGEF11 GTRAP48, PDZ-RHOGEF Rho guanine nucleotide exchange factor 11 rho guanine nucleotide exchange factor 11|Rho guanine exchange factor (GEF) 11|Rho guanine nucleotide exchange factor (GEF) 11|RhoA-specific guanine nucleotide exchange factor|RhoGEF glutamate transport modulator|glutamate transporter EAAT4-associated protein 48

For more info on ARHGEF11, check out the ARHGEF11 Infographic

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In this infographic, you will see the following information for ARHGEF11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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