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- Table of Contents
Facts about Rho guanine nucleotide exchange factor 11.
Involved in neurotrophin-induced neurite outgrowth. .
Human | |
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Gene Name: | ARHGEF11 |
Uniprot: | O15085 |
Entrez: | 9826 |
Belongs to: |
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No superfamily |
DKFZp667F1223; glutamate transporter EAAT4-associated protein 48; GTRAP48; KIAA0380rho guanine nucleotide exchange factor 11; PDZ-RHOGEF; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; RhoA-specific guanine nucleotide exchange factor; RhoGEF glutamate transport modulator
Mass (kDA):
167.704 kDA
Human | |
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Location: | 1q23.1 |
Sequence: | 1; NC_000001.11 (156934840..157046903, complement) |
Ubiquitously expressed.
Cytoplasm. Membrane. Translocated to the membrane upon stimulation.
PMID: 10526156 by Ruemenapp U., et al. Rho-specific binding and guanine nucleotide exchange catalysis by KIAA0380, a dbl family member.
PMID: 10026210 by Fukuhara S., et al. A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho.