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Product Info Summary
| SKU: | A04962 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IF, ICC, WB |
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Product info
Product Name
Anti-Aspartoacylase ASPA Antibody
SKU/Catalog Number
A04962
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Aspartoacylase ASPA Antibody catalog # A04962. Tested in WB,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Aspartoacylase ASPA Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04962)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human ALDH1A2
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04962 is reactive to ASPA in Human, Mouse, Rat
Applications
A04962 is guaranteed for IF, ICC, WB Boster Guarantee
Observed Molecular Weight
111 kDa
Calculated molecular weight
35.735kDa
Background of ASPA
Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Colicelli J., Proc. Natl. Acad. Sci. U.S.A. 88:2913-2917(1991).
Han L., Mol. Cell. Biol. 15:1318-1323(1995).
Han L., Proc. Natl. Acad. Sci. U.S.A. 94:4954-4959(1997)
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
ICC/IF: 1:50-1:100
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For ASPA (Source: Uniprot.org, NCBI)
Gene Name
ASPA
Full Name
Aspartoacylase
Weight
35.735kDa
Superfamily
AspA/AstE family
Alternative Names
ACY-2; ACY2aminoacylase 2; Aminoacylase-2; ASPaminoacylase-2; aspartoacylase (aminoacylase 2, Canavan disease); aspartoacylase; EC 3.5.1.15 ASPA ACY2, ASP aspartoacylase aspartoacylase|ACY-2|aminoacylase 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ASPA, check out the ASPA Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ASPA: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Aspartoacylase ASPA Antibody (A04962)
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No publications found for A04962
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