Anti-ATM interactor ATMIN Antibody

Product Name

Anti-ATM interactor ATMIN Antibody

View all ATMIN Antibodies

SKU/Catalog Number

A06542

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-ATM interactor ATMIN Antibody (Catalog # A06542). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

ATMIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-ATM interactor ATMIN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06542)

Host

Rabbit

Contents

ATMIN Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

ATMIN antibody was raised against a 19 amino acid peptide near the amino terminus of human ATMIN. The immunogen is located within amino acids 200 - 250 of ATMIN.

Cross-reactivity

ATMIN antibody is human, mouse and rat reactive. At least three isoforms of ATMIN are known to exist.

Reactive Species

A06542 is reactive to ATMIN in Human, Mouse, Rat

Observed Molecular Weight

68 kDa

Calculated molecular weight

88.3 kDa

Background of ATMIN

The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51 (1). ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects (2). It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression (3).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A06542 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

ATMIN antibody can be used for detection of ATMIN by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunocytochemistry at 5 μg/mL. For Immunoflorescence start at 2.5 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information ATMIN

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