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Product Info Summary
| SKU: | A06542 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-ATM interactor ATMIN Antibody
SKU/Catalog Number
A06542
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ATM interactor ATMIN Antibody (Catalog # A06542). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ATMIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-ATM interactor ATMIN Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06542)
Host
Rabbit
Contents
ATMIN Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
ATMIN antibody was raised against a 19 amino acid peptide near the amino terminus of human ATMIN. The immunogen is located within amino acids 200 - 250 of ATMIN.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ATMIN antibody is human, mouse and rat reactive. At least three isoforms of ATMIN are known to exist.
Reactive Species
A06542 is reactive to ATMIN in Human, Mouse, Rat
Applications
A06542 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
88.348kDa
Background of ASCIZ
The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51 (1). ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects (2). It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ATMIN antibody can be used for detection of ATMIN by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunocytochemistry at 5 μg/mL. For Immunoflorescence start at 2.5 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ATMIN in 293 cell lysate with ATMIN antibody at (A) 1 and (B) 2 μg/ml.
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Immunocytochemistry of ATMIN in A431 cells with ATMIN antibody at 5 μg/mL.
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Immunofluorescence of ATMIN in A431 cells with ATMIN antibody at 2.5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ATMIN (Source: Uniprot.org, NCBI)
Gene Name
ATMIN
Full Name
ATM interactor
Weight
88.348kDa
Alternative Names
ASCIZ; ATM INteracting protein; ATM interactor; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein; DKFZp779K1455; FLJ50270; FLJ61620; FLJ76795; KIAA0431; zinc finger protein 822; ZNF822 ATMIN ASCIZ, ZNF822 ATM interactor ATM interactor|ATM INteracting protein|ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein|ATM/ATR-substrate CHEK2-interacting zinc finger protein|ATM/ATR-substrate CHK2-interacting zinc finger protein|zinc finger protein 822
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ATMIN, check out the ATMIN Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ATMIN: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ATM interactor ATMIN Antibody (A06542)
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No publications found for A06542
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Customer Reviews
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