Anti-ATP1B2 Antibody

Product Name

Anti-ATP1B2 Antibody

View all ATPase Na+/K+ beta 2 Antibodies

SKU/Catalog Number

A07027

Size

100ul

Form

Liquid

Description

Boster Bio Anti-ATP1B2 Antibody catalog # A07027. Tested in WB,ICC/IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ATP1B2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07027)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human TSEN54.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A07027 is reactive to ATP1B2 in Human, Mouse, Rat

Applications

A07027 is guaranteed for IF, ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

33.367kDa

Background of ATPase Na+/K+ beta 2

Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.

Zody M.C., Nature 440:1045-1049(2006).
Paushkin S.V., Cell 117:311-321(2004).
Ota T., Nat. Genet. 36:40-45(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000
ICC/IF: 1:50-1:200

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-ATP1B2 Antibody A07027

Western blot analysis of extracts of various cells

Gene/Protein Information For ATP1B2 (Source: Uniprot.org, NCBI)

Alternative Names

adhesion molecule on glia; AMOGsodium/potassium-dependent ATPase beta-2 subunit; ATPase, Na+/K+ transporting, beta 2 polypeptide; Na, K-ATPase beta-2 polypeptide; Sodium/potassium-dependent ATPase subunit beta-2; sodium/potassium-transporting ATPase beta-2 chain; sodium/potassium-transporting ATPase subunit beta-2 ATP1B2 AMOG ATPase Na+/K+ transporting subunit beta 2 sodium/potassium-transporting ATPase subunit beta-2|ATPase, Na+/K+ transporting, beta 2 polypeptide|Na, K-ATPase beta-2 polypeptide|adhesion molecule in glia|adhesion molecule on glia|sodium pump subunit beta-2|sodium-potassium ATPase subunit beta 2 (non-catalytic)|sodium/potassium-dependent ATPase beta-2 subunit|sodium/potassium-dependent ATPase subunit beta-2|sodium/potassium-transporting ATPase beta-2 chain

For more info on ATP1B2, check out the ATP1B2 Infographic

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In this infographic, you will see the following information for ATP1B2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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