Product Info Summary
SKU: | A01538 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-Battenin CLN3 Antibody
SKU/Catalog Number
A01538
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Battenin CLN3 Antibody catalog # A01538. Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Battenin CLN3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01538)
Host
Rabbit
Contents
Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human CLN3 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01538 is reactive to CLN3 in Human
Applications
A01538 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
47.623kDa
Background of CLN3
Isoform 1:Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.Isoform 3:Promotes cell to cell and cell to substratum adhesion, increases the cell proliferation rate and leads to cytokeratin hyper-expression (when overexpressed in HeLa cells).
Heiss N.S., Nat. Genet. 19:32-38(1998).
Knight S.W., Am. J. Hum. Genet. 65:50-58(1999).
Hassock S., Genomics 55:21-27(1999).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-2000 ELISA 1:5000-20000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For CLN3 (Source: Uniprot.org, NCBI)
Gene Name
CLN3
Full Name
Battenin
Weight
47.623kDa
Superfamily
battenin family
Alternative Names
Batten disease protein; Batten, Spielmeyer-Vogt disease; battenin; BTSMGC102840; ceroid-lipofuscinosis, neuronal 3; JNCL; Protein CLN3 CLN3 BTN1, BTS, JNCL CLN3 lysosomal/endosomal transmembrane protein, battenin battenin|CLN3, battenin|batten disease protein|ceroid-lipofuscinosis, neuronal 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CLN3, check out the CLN3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CLN3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Battenin CLN3 Antibody (A01538)
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No publications found for A01538
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