|Product Name||Anti-Beta-Tubulin Antibody (Monoclonal, TUB 2.1)|
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Mouse IgG monoclonal antibody for beta-Tubulin detection. Tested with WB, IHC-P in Human,mouse,rat. No cross reactivity with other proteins.|
|Cite This Product||Anti-Beta-Tubulin Antibody (Monoclonal, TUB 2.1) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1112)|
|Immunogen||Tubulin from rat brain.|
|Reactivity||Human, Mouse, Rat|
Assay Dilutions Overview
Western blot, 2μg/ml, Human, mouse, rat
Boster's Secondary Antibodies And IHC, WB Kits
The following reagents are used to generate the images below.Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
Images And Assay Conditions
Anti-beta-Tubulin antibody (monoclonal), MA1112, Western blotting
WB: Rat Skeletal Muscle Tissue Lysate
Anti-beta-Tubulin antibody (monoclonal), MA1112, IHC(P)
IHC(P): Human Mammary Cancer Tissue
Protein Target Info (Source: Uniprot.org)
|Protein Name||Tubulin beta-1 chain|
|Tissue Specificity||Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins. .|
|Alternative Names||Tubulin beta-1 chain;TUBB1;|
|Subcellular Localization||Cytoplasm, cytoskeleton .|
|Molecular Weight||50327 MW|
*if product is indicated to react with multiple species, protein info is based on the human gene.
|Protein Function||Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). .|
|Background||Tubulin beta(TUBB) was derived from its corresponding mRNA with a molecular weight of about 55,000. TUBB gene contains 4 exons and located in the HLA class I region at 6p21.3. Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations.|
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