Anti-Betatrophin ANGPTL8 Antibody

Angiopoietin-like protein 8/Betatrophin antibody

Boster Bio Anti-Betatrophin ANGPTL8 Antibody (Catalog # A02471-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A02471-1
Size: 0.1 mg
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IF, IHC-P, WB

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Product Name

Anti-Betatrophin ANGPTL8 Antibody

View all Angiopoietin-like protein 8/Betatrophin Antibodies

SKU/Catalog Number

A02471-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Betatrophin ANGPTL8 Antibody (Catalog # A02471-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Betatrophin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-Betatrophin ANGPTL8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02471-1)

Host

Rabbit

Contents

Betatrophin antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

SK7

Isotype

IgG

Immunogen

Betatrophin antibody was raised against a 16 amino acid peptide near the amino terminus of human Betatrophin. The immunogen is located within amino acids 40 - 90 of Betatrophin.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Betatrophin antibody is human, mouse and rat reactive. At least three isoforms of Betatrophin are known to exist; this antibody will detect the two largest isoforms.

Reactive Species

A02471-1 is reactive to ANGPTL8 in Human, Mouse, Rat

Applications

A02471-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

22.105kDa

Background of Angiopoietin-like protein 8/Betatrophin

The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels (1,2). Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis (3).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Betatrophin antibody can be used for detection of Betatrophin by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse and rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For ANGPTL8 (Source: Uniprot.org, NCBI)

Gene Name

ANGPTL8

Full Name

Angiopoietin-like protein 8

Weight

22.105kDa

Superfamily

ANGPTL8 family

Alternative Names

Angiopoietin like Protein 8; Angiopoietin-like Protein 8; ANGPTL8; Betatrophin; C19orf80; chromosome 19 open reading frame 80; Gm6484; hepatocellular carcinoma-associated gene TD26; hepatocellular carcinoma-associated protein TD26; Lipasin; PRO1185; PVPA599; RIFL; TD26; UNQ599 ANGPTL8 C19orf80, PRO1185, PVPA599, RIFL, TD26 angiopoietin like 8 angiopoietin-like protein 8|betatrophin variant 1|betatrophin variant 2|hepatocellular carcinoma-associated gene TD26|hepatocellular carcinoma-associated protein TD26|lipasin|refeeding-induced fat and liver protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ANGPTL8, check out the ANGPTL8 Infographic

ANGPTL8 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ANGPTL8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02471-1-0.1 mg

0.1 mg

$449

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