Product Info Summary
SKU: | A06968 |
---|---|
Size: | 100 µl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Bone morphogenetic protein 10 BMP10 Antibody
SKU/Catalog Number
A06968
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-Bone morphogenetic protein 10 BMP10 Antibody (Catalog # A06968). Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Bone morphogenetic protein 10 BMP10 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06968)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from Internal of human BMP10.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06968 is reactive to Bmp10 in Human
Applications
A06968 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
47.888kDa
Background of BMP-10
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Celeste A.J., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., Nature 434:724-731(2005).
Mazerbourg S., J. Biol. Chem. 280:32122-32132(2005).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from Jurkat cells, using BMP10 antibody A06968.
Protein Target Info & Infographic
Gene/Protein Information For Bmp10 (Source: Uniprot.org, NCBI)
Gene Name
Bmp10
Full Name
Bone morphogenetic protein 10
Weight
47.888kDa
Superfamily
TGF-beta family
Alternative Names
BMP10; BMP-10; bone morphogenetic protein 10; MGC126783 Bmp10|b2b2711C, b2b2711Clo|bone morphogenetic protein 10|bone morphogenetic protein 10|BMP-10
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Bmp10, check out the Bmp10 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Bmp10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Bone morphogenetic protein 10 BMP10 Antibody (A06968)
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No publications found for A06968
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