This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
CDCA8 antibody (A06612) performs well in ELISA, IF, WB and shows reactivity with Human, Mouse, Rat.
- Validated for inter-lot consistency, specificity, and reproducibility
- Committed to quality since 1993
Filter:
Immunofluorescence of CDCA8 in rat kidney tissue with CDCA8 antibody at 20 μg/mL.
Bundle Save
Anti-Borealin CDCA8 Antibody
CDCA8 antibody
| Reactive Species | Host | Application |
|---|---|---|
| Human, Mouse, Rat | Rabbit | ELISA, IF, WB |
Recommend Dilution
Application
Dilution
Species
CDCA8 antibody can be used for detection of CDCA8 by Western blot at 1 and 2 μg/mL. Antibody can also be used for immunoflourescence starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
* It is recommended to optimize the amount of this reagent in each experimental system to achieve the best results.
Product Information
Product Name
Anti-Borealin CDCA8 Antibody
View all CDCA8 Antibodies
View all CDCA8 Antibodies
Form
Liquid
Uniprot
Gene ID
Storage & Handling
CDCA8 antibody can be stored at 4°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Host
Rabbit
Contents
CDCA8 Antibody is supplied in PBS containing ≤0.09% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CDCA8 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of the human CDCA8. The immunogen is located within the first 50 amino acids of CDCA8.
Observed Molecular Weight
68 kDa
Calculated Molecular Weight
31.3 kDa
Background of CDCA8
CDCA8 is a component of a chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle. The chromosomal passenger complex, which includes Survivin, CDCA8, INCENP and Aurora-B, is known to play crucial roles during mitosis and cell division. It was found that CDCA8 interacting with Aurora-B, INCENP and Survivin, increases during G2/M phase and then reduces after exit from M phase. CDCA8 is cell cycle regulated, down-regulated in response to p53/Rb-signaling, and up-regulated in many types of cancerous tissues. In Drosophila cells, inactivation of CDCA8 results in polyploidy, delayed mitosis and abnormal tissue development, indicating its critical role for cell proliferation. Recent studies show that CDCA8 is essential for cell proliferation during early embryonic development, and its early embryonic lethality cannot be rescued by the loss of p53. Its aberrant expression is linked to a poor prognosis for gastric cancer.
Cite This Product
Anti-Borealin CDCA8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06612)
Review
Have you used Anti-Borealin CDCA8 Antibody?
Submit a review and receive $370 in product credits, a $185 Amazon gift card, or our carefully curated gift bundles.
Product Promise
We promise Anti-Borealin CDCA8 Antibody performs excellently in relevant applications for ELISA, IF, WB. If it doesn't perform as promised, we will refund the product. Learn more
In stock
Order Product
A06612
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$481.00
Troubleshooting
Boster Guarantee
Guaranteed product quality
We promise all of our products perform as described in datasheets.
This product is for Research Use Only. Not for use in diagnostic procedures.
Update date:
Oct 4, 2026