Product Info Summary
SKU: | A03754 |
---|---|
Size: | 100μl |
Reactive Species: | Human |
Host: | Mouse |
Application: | WB |
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Product info
Product Name
Anti-BPTF/Falz Monoclonal Antibody
SKU/Catalog Number
A03754
Size
100μl
Form
Liquid
Description
Boster Bio Anti-BPTF/Falz Monoclonal Antibody catalog # A03754. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-BPTF/Falz Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03754)
Host
Mouse
Contents
Ascitic fluid containing 0.03% sodium azide.
Clonality
Monoclonal
Clone Number
2F1
Isotype
IgG
Immunogen
Purified recombinant fragment of human BPTF expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A03754 is reactive to BPTF in Human
Applications
A03754 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
39 kDa
Calculated molecular weight
338.262kDa
Background of BPTF/FALZ
CAND1 is also known as TIP120A, and TATA-binding protein-interacting protein 120A. The SCF complex consists of the invariable components Skp1, Cul1, and Rbx1 as well as a variable F-box protein, and functions as an E3 ubiquitin ligase. E3 ubiquitin ligases regulate various physiological processes. CAND1 binds to Cul1 and potentially regulates the SCF complex. CAND1 physically associates with Cul1 in the nucleus and this interaction is mediated by a central region of Cul1 distinct from its binding sites for Skp1 and Rbx1. CAND1 selectively binds to unneddylated CUL1 and is dissociated by CUL1 neddylation. CAND1 forms a ternary complex with CUL1 and ROC1.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB, 1:500-1:2000
Validation Images & Assay Conditions
Click image to see more details
Western Blot (WB) analysis using BPTF Monoclonal antibody against HEK293 (1) and BPTF (AA: 503-670)-hIgGFc transfected HEK293 (2) cell lysate.
Click image to see more details
ELISA analysis of BPTF antibody.
Protein Target Info & Infographic
Gene/Protein Information For BPTF (Source: Uniprot.org, NCBI)
Gene Name
BPTF
Full Name
Nucleosome-remodeling factor subunit BPTF
Weight
338.262kDa
Superfamily
PBTF family
Alternative Names
bromodomain and PHD domain transcription factor; Bromodomain and PHD finger-containing transcription factor; bromodomain PHD finger transcription factor; EC 3.6.1; EC 6.2.1.5; FAC1fetal Alz-50 reactive clone 1; FALZnucleosome-remodeling factor subunit BPTF; Fetal Alz-50 clone 1 protein; Fetal Alzheimer antigennucleosome remodeling factor, large subunit; NURF301 BPTF FAC1, FALZ, NEDDFL, NURF301 bromodomain PHD finger transcription factor nucleosome-remodeling factor subunit BPTF|bromodomain and PHD domain transcription factor|bromodomain and PHD finger-containing transcription factor|fetal Alz-50 clone 1 protein|fetal Alz-50 reactive clone 1|fetal Alzheimer antigen|nucleosome remodeling factor, large subunit
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BPTF, check out the BPTF Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BPTF: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-BPTF/Falz Monoclonal Antibody (A03754)
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No publications found for A03754
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Customer Reviews
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Customer Q&As
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3 Customer Q&As for Anti-BPTF/Falz Monoclonal Antibody
Question
I see that the anti-BPTF/Falz Monoclonal antibody A03754 works with WB, what is the protocol used to produce the result images on the product page?
Verified Customer
Verified customer
Asked: 2020-05-05
Answer
You can find protocols for WB on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]
Boster Scientific Support
Answered: 2020-05-05
Question
I would like to test anti-BPTF/Falz Monoclonal antibody A03754 on human cervix carcinoma erythroleukemia for research purposes, then I may be interested in using anti-BPTF/Falz Monoclonal antibody A03754 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
M. Moore
Verified customer
Asked: 2019-10-24
Answer
The products we sell, including anti-BPTF/Falz Monoclonal antibody A03754, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2019-10-24
Question
We are currently using anti-BPTF/Falz Monoclonal antibody A03754 for human tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on zebrafish tissues as well?
A. Walker
Verified customer
Asked: 2017-07-14
Answer
The anti-BPTF/Falz Monoclonal antibody (A03754) has not been validated for cross reactivity specifically with zebrafish tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in zebrafish you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2017-07-14