Anti-BPTF/Falz Monoclonal Antibody
Mouse Monoclonal Antibody for BPTF Antibody (BPTF) detection. Tested with WB in Human.
|Product Name||Anti-BPTF/Falz Monoclonal Antibody
See all BPTF primary antibodies, ELISA kits and proteins
|Storage & Handling||Store at -20°C for one year, at 4°C for one month. We suggest the antibody be aliquotted into small vials and stored frozen at -20°C upon receiving. Avoid repeated freezing and thawing.|
|Description||Monoclonal clone# G2 antibody for FALZ/BPTF detection. Host: Mouse.Size: 100μl. Tested applications: WB. Reactive species: Human. FALZ/BPTF information: Molecular Weight: 338262 MW; Subcellular Localization: Cytoplasm. Nucleus. In brains of Alzheimer disease patients, present in a subset of amyloid- containing plaques; Tissue Specificity: Ubiquitously expressed, with highest levels in testis. Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex (at protein level).|
|Cite This Product||Anti-BPTF/Falz Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03754)|
|Specificity||Anti-BPTF/Falz Monoclonal Antibody (A03754) reacts with Human BPTF, in native form and recombinant. Superfamily members of BPTF are not reactive to A03754.|
|Contents/Buffer||Ascitic fluid containing 0.03% sodium azide.|
|Immunogen||Purified recombinant fragment of human BPTF expressed in E. Coli.|
Our Boster Quality Guarantee for Anti-BPTF/Falz Monoclonal Antibody covers its use in the following applications.
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
Assay Dilutions Overview
Images And Assay Conditions
Western Blot (WB) analysis using BPTF Monoclonal antibody against HEK293 (1) and BPTF (AA: 503-670)-hIgGFc transfected HEK293 (2) cell lysate.
ELISA analysis of BPTF antibody.
Protein Target Info (Source: Uniprot.org)
|Protein Name||Nucleosome-remodeling factor subunit BPTF|
|Tissue Specificity||Ubiquitously expressed, with highest levels in testis. Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex (at protein level). .|
|Alternative Names||Nucleosome-remodeling factor subunit BPTF;Bromodomain and PHD finger-containing transcription factor;Fetal Alz-50 clone 1 protein;Fetal Alzheimer antigen;BPTF;FAC1, FALZ;|
|Subcellular Localization||Cytoplasm. Nucleus. In brains of Alzheimer disease patients, present in a subset of amyloid- containing plaques.|
|Molecular Weight||338262 MW|
*if product is indicated to react with multiple species, protein info is based on the human gene.
|Protein Function||Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.|
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