Anti-BPTF/Falz Monoclonal Antibody

BPTF/FALZ antibody

Boster Bio Anti-BPTF/Falz Monoclonal Antibody catalog # A03754. Tested in WB applications. This antibody reacts with Human.

Product Info Summary

SKU: A03754
Size: 100μl
Reactive Species: Human
Host: Mouse
Application: WB

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Product Name

Anti-BPTF/Falz Monoclonal Antibody

View all BPTF/FALZ Antibodies

SKU/Catalog Number

A03754

Size

100μl

Form

Liquid

Description

Boster Bio Anti-BPTF/Falz Monoclonal Antibody catalog # A03754. Tested in WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-BPTF/Falz Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03754)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

2F1

Isotype

IgG

Immunogen

Purified recombinant fragment of human BPTF expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A03754 is reactive to BPTF in Human

Applications

A03754 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

338.262kDa

Background of BPTF/FALZ

CAND1 is also known as TIP120A, and TATA-binding protein-interacting protein 120A. The SCF complex consists of the invariable components Skp1, Cul1, and Rbx1 as well as a variable F-box protein, and functions as an E3 ubiquitin ligase. E3 ubiquitin ligases regulate various physiological processes. CAND1 binds to Cul1 and potentially regulates the SCF complex. CAND1 physically associates with Cul1 in the nucleus and this interaction is mediated by a central region of Cul1 distinct from its binding sites for Skp1 and Rbx1. CAND1 selectively binds to unneddylated CUL1 and is dissociated by CUL1 neddylation. CAND1 forms a ternary complex with CUL1 and ROC1.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

Gene/Protein Information For BPTF (Source: Uniprot.org, NCBI)

Gene Name

BPTF

Full Name

Nucleosome-remodeling factor subunit BPTF

Weight

338.262kDa

Superfamily

PBTF family

Alternative Names

bromodomain and PHD domain transcription factor; Bromodomain and PHD finger-containing transcription factor; bromodomain PHD finger transcription factor; EC 3.6.1; EC 6.2.1.5; FAC1fetal Alz-50 reactive clone 1; FALZnucleosome-remodeling factor subunit BPTF; Fetal Alz-50 clone 1 protein; Fetal Alzheimer antigennucleosome remodeling factor, large subunit; NURF301 BPTF FAC1, FALZ, NEDDFL, NURF301 bromodomain PHD finger transcription factor nucleosome-remodeling factor subunit BPTF|bromodomain and PHD domain transcription factor|bromodomain and PHD finger-containing transcription factor|fetal Alz-50 clone 1 protein|fetal Alz-50 reactive clone 1|fetal Alzheimer antigen|nucleosome remodeling factor, large subunit

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on BPTF, check out the BPTF Infographic

BPTF infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for BPTF: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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3 Customer Q&As for Anti-BPTF/Falz Monoclonal Antibody

Question

I see that the anti-BPTF/Falz Monoclonal antibody A03754 works with WB, what is the protocol used to produce the result images on the product page?

Verified Customer

Verified customer

Asked: 2020-05-05

Answer

You can find protocols for WB on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]

Boster Scientific Support

Answered: 2020-05-05

Question

I would like to test anti-BPTF/Falz Monoclonal antibody A03754 on human cervix carcinoma erythroleukemia for research purposes, then I may be interested in using anti-BPTF/Falz Monoclonal antibody A03754 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

M. Moore

Verified customer

Asked: 2019-10-24

Answer

The products we sell, including anti-BPTF/Falz Monoclonal antibody A03754, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2019-10-24

Question

We are currently using anti-BPTF/Falz Monoclonal antibody A03754 for human tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human. Is it true that the antibody can work on zebrafish tissues as well?

A. Walker

Verified customer

Asked: 2017-07-14

Answer

The anti-BPTF/Falz Monoclonal antibody (A03754) has not been validated for cross reactivity specifically with zebrafish tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in zebrafish you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2017-07-14

Order DetailsPrice
A03754

100uL

$399

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