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Product Info Summary
| SKU: | A03518 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-C-C chemokine receptor type 8 CCR8 Antibody
SKU/Catalog Number
A03518
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-C-C chemokine receptor type 8 CCR8 Antibody (Catalog # A03518). Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
CCR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-C-C chemokine receptor type 8 CCR8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03518)
Host
Rabbit
Contents
CCR8 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CCR8 antibody was raised against a 19 amino acid peptide near the center of human CCR8. The immunogen is located within amino acids 170 - 220 of CCR8.
Reactive Species
A03518 is reactive to CCR8 in Human
Observed Molecular Weight
68 kDa
Background of CCR8
CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03518 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CCR8 antibody can be used for detection of CCR8 by Western blot 0.5 μg/mL. An approximately 50 kDa band can be detected.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CCR8 in human spleen lysate with CCR8 antibody at 1:500 dilution.
Specific Publications For Anti-C-C chemokine receptor type 8 CCR8 Antibody (A03518)
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