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Product Info Summary
| SKU: | A08841 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-C2 domain-containing protein 3 C2CD3 Antibody
SKU/Catalog Number
A08841
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-C2 domain-containing protein 3 C2CD3 Antibody (Catalog # A08841). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
C2CD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-C2 domain-containing protein 3 C2CD3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08841)
Host
Rabbit
Contents
C2CD3 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
C2CD3 antibody was raised against an 18 amino acid peptide near the center of human C2CD3. The immunogen is located within amino acids 1490 - 1540 of C2CD3.
Cross-reactivity
C2CD3 antibody is human, mouse and rat reactive.
Reactive Species
A08841 is reactive to C2CD3 in Human, Mouse, Rat
Observed Molecular Weight
68 kDa
Calculated molecular weight
260.4 kDa
Background of C2CD3
C2CD3, a putative calcium-dependent lipid-binding protein, is an essential regulator of intracellular transduction of the Hedgehog signal (1). It is localized at the basal body of cilia, mediates calcium-dependent vesicular transport and/or recruitment of proteins and regulates cilium biogenesis by promoting the assembly of centriolar distal appendages critical for docking ciliary vesicles and recruiting other essential ciliogenic proteins (2,3). C2CD3 directly promotes centriole elongation and OFD1 acts as a negative regulator of C2CD3 (4,5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08841 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
C2CD3 antibody can be used for detection of C2CD3 by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of C2CD3 in EL4 cell lysate with C2CD3 antibody at (A) 1 and (B) 2 μg/ml.
Specific Publications For Anti-C2 domain-containing protein 3 C2CD3 Antibody (A08841)
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