Product Info Summary
SKU: | M07171 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Mouse |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Casein Kinase alpha CSNK1A1 Monoclonal Antibody
View all Casein Kinase 1 alpha Antibodies
SKU/Catalog Number
M07171
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Casein Kinase alpha CSNK1A1 Monoclonal Antibody catalog # M07171. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Casein Kinase alpha CSNK1A1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M07171)
Host
Mouse
Contents
Ascitic fluid containing 0.03% sodium azide.
Clonality
Monoclonal
Clone Number
3C10F7 / 3C10G5 / PMC01 / 4D12B3 / 3C10F7C11
Isotype
IgG
Immunogen
Purified recombinant fragment of Casein Kinase Ialpha expressed in E. Coli.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M07171 is reactive to CSNK1A1 in Human
Applications
M07171 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
38.915kDa
Background of Casein Kinase 1 alpha
Tissue inhibitor of metalloproteinase-4 (TIMP-4) is member of the TIMP family of inhibitors of matrix metalloproteinase (MMP) activities. In addition, TIMPs have non-MMP associated functions, including roles in growth promotion, apoptosis, and angiogenesis. All four members of the TIMP gene family form a similar secondary structure due to the formation of six highly conserved disulfide bonds. It has been reported that some TIMPs, TIMP4 included, can bind a tetraspanin in the plasma membrane, initiating an intra-cellular signaling cascade. Elevated levels of TIMP4 have been associated with breast cancer progression and heart disease.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:200-1:1000
ELISA 1:10000
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of CSNK1A1 using Anti-Casein Kinase alpha CSNK1A1 Monoclonal Antibody (M07171).
Immunohistochemistry (IHC) analysis of paraffin-embedded Human Liver Tissue (A)Click image to see more details
Figure 1. Western blotting validation for Anti-Casein Kinase alpha CSNK1A1 Monoclonal Antibody M07171
Western Blot (WB) analysis using Casein Kinase Ialpha Monoclonal Antibody against truncated CK1 recombinant protein.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For CSNK1A1 (Source: Uniprot.org, NCBI)
Gene Name
CSNK1A1
Full Name
Casein kinase I isoform alpha
Weight
38.915kDa
Superfamily
protein kinase superfamily
Alternative Names
Casein Kinase 1 alpha; casein kinase 1, alpha 1; casein kinase I isoform alpha; CK1CKI-alpha; CSNK1A1; down-regulated in lung cancer; EC 2.7.11.1; HLCDGP1; PRO2975 CSNK1A1 CK1, CK1a, CKIa, HEL-S-77p, HLCDGP1, PRO2975 casein kinase 1 alpha 1 casein kinase I isoform alpha|CKI-alpha|clock regulator kinase|down-regulated in lung cancer|epididymis secretory sperm binding protein Li 77p
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CSNK1A1, check out the CSNK1A1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CSNK1A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Casein Kinase alpha CSNK1A1 Monoclonal Antibody (M07171)
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No publications found for M07171
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