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- Table of Contents
CSNK1A1 Antibodies
AND CSNK1A1 ELISA kits, CSNK1A1 Proteins
Many biological assays use antibodies to detect CSNK1A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CSNK1A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CSNK1A1 antibodies...
Designing a Western blot for CSNK1A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CSNK1A1 Western Blot GuideCSNK1A1 Infographic by Boster Bio
All CSNK1A1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9693
100 μg/vial
Cat # PB9693
100 μg/vial
Human
$628
Cat # LS001452
20 µg, 100 µg
Cat # LS001452
20 µg, 100 µg
Human, Mouse, Rat
ELISA
$540
Cat # EKC2560
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2560
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2332
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2332
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1727
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1727
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A14331-1
100ul
Cat # A14331-1
100ul
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A07171Y321
100ul
Cat # A07171Y321
100ul
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A07171Y294
100ul
Cat # A07171Y294
100ul
CSNK1A1 Overview
Facts about Casein kinase I isoform alpha.
Casein kinase I isoform alpha (CSNK1A1)
It can phosphorylate a large number of proteins. Participates in Wnt signaling.
Phosphorylates CTNNB1 at'Ser-45'. May phosphorylate PER1 and PER2.
Gene Information
| Human | |
|---|---|
| Gene Name: | CSNK1A1 |
| Uniprot: | P48729 |
| Entrez: | 1452 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
Casein Kinase 1 alpha; casein kinase 1, alpha 1; casein kinase I isoform alpha; CK1CKI-alpha; CSNK1A1; down-regulated in lung cancer; EC 2.7.11.1; HLCDGP1; PRO2975
Molecular Weight
Mass (kDA):
38.915 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q32 |
| Sequence: | 5; NC_000005.10 (149492982..149551439, complement) |
Subcellular Localizations
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus speckle. Cytoplasm, cytoskeleton, cilium basal body. Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. Also recruited to the keratin cytoskeleton (PubMed:23902688).
Diseases
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Malignant Neoplasm Of Lung
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Carcinoma
- Cell Invasion
- Lung Neoplasms
- Non-small Cell Lung Carcinoma
- Adenoma
- Malnutrition
- Metastatic Malignant Neoplasm To The Lymph Node
Interacting Proteins
- CARD11
- CRBN
- LRRK2
- MALT1
- MDM2
- MDM4
- RIPK1
Pathways
- Senescence
- Regulation Of Macroautophagy
- Macroautophagy
- Cell Cycle
- Cell Motility
- Cellular Senescence
- Cellular Homeostasis
- Atp/adp Exchange
PTMs
Research Areas
- Protein Kinase
- Wnt Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CSNK1A1
bosterbio.com/bosterbio-gene-info-cards/CSNK1A1
References
PMID: 8050587 by Tapia C., et al. Cloning and chromosomal localization of the gene coding for human protein kinase CK1.
PMID: 7797465 by Fish K.J., et al. Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family.