Anti-Caspase-5/CASP5 Antibody Picoband™

Caspase 5 antibody

Boster Bio Anti-Caspase-5/CASP5 Antibody Picoband™ catalog # A05259-4. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A05259-4
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, Flow Cytometry, IF, IHC, ICC, WB

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Product Name

Anti-Caspase-5/CASP5 Antibody Picoband™

View all Caspase 5 Antibodies

SKU/Catalog Number

A05259-4

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Caspase-5/CASP5 Antibody Picoband™ catalog # A05259-4. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Caspase-5/CASP5 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05259-4)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human Caspase-5/CASP5 recombinant protein (Position: D137-N434).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A05259-4 is reactive to CASP5 in Human, Mouse, Rat

Applications

A05259-4 is guaranteed for ELISA, Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

50 kDa

Calculated molecular weight

49.736kDa

Background of Caspase 5

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5μg/ml, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Flow Cytometry, 1-3μg/1x106 cells, Human
Direct ELISA, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For CASP5 (Source: Uniprot.org, NCBI)

Gene Name

CASP5

Full Name

Caspase-5

Weight

49.736kDa

Superfamily

peptidase C14A family

Alternative Names

CASP5; CASP-5; caspase 5, apoptosis-related cysteine peptidase; caspase 5, apoptosis-related cysteine protease; Caspase5; Caspase-5; EC 3.4.22; EC 3.4.22.58; ICE(rel)III; ICE(rel)-III; ICEREL-III; ICH3; ICH-3; MGC141966; Protease ICH-3; Protease TY; TY protease CASP5 ICE(rel)III, ICEREL-III, ICH-3 caspase 5 caspase-5|TY protease|caspase 5 variant X1|caspase 5, apoptosis-related cysteine peptidase|caspase 5, apoptosis-related cysteine protease|protease ICH-3|protease TY

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CASP5, check out the CASP5 Infographic

CASP5 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CASP5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A05259-4

100μg

$370
A05259-4-10ug

10μg sample (liquid)

$99
A05259-4-Biotin

100 μg Biotin conjugated

$570
A05259-4-Cy3

100 μg Cy3 conjugated

$570
A05259-4-Dylight488

100 μg Dylight488 conjugated

$570
A05259-4-Dylight550

100 μg Dylight550 conjugated

$570
A05259-4-Dylight594

100 μg Dylight594 conjugated

$570
A05259-4-FITC

100 μg FITC conjugated

$570
A05259-4-HRP

100 μg HRP conjugated

$570
A05259-4-APC

100 μg APC conjugated

$670
A05259-4-PE

100 μg PE conjugated

$670
A05259-4-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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A05259-4
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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