Anti-Cathepsin L Ctsl Antibody (Monoclonal, 35C61)

Product Name

Anti-Cathepsin L Ctsl Antibody (Monoclonal, 35C61)

View all Ctsl Antibodies

SKU/Catalog Number

M01589-2
BM1578 is an alternative SKU for this antibody, used in previous lots.

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Cathepsin L Ctsl Antibody (Monoclonal, 35C61) catalog # M01589-2. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Cathepsin L Ctsl Antibody (Monoclonal, 35C61) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01589-2)

Host

Mouse

Contents

Mouse IgG in stabilizing components, 1.2% sodium acetate and 0.01mg NaN3.
This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Monoclonal

Clone Number

35C61

Isotype

Mouse IgG1

Immunogen

Procathepsin L isolated from the human lung cancer cell line EPLC 32M1.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

M01589-2 is reactive to Ctsl in Human, Mouse, Rat

Calculated molecular weight

37.7 kDa

Background of Ctsl

Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M01589-2 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Frozen Section), 4μg/ml, Human, mouse, rat, -
Western blot, 0.1-0.5μg/ml, Human, mouse, rat

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

See full target information Ctsl

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