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Product Info Summary
|Reactive Species:||Human, Mouse, Rat|
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Anti-Cathepsin L Ctsl Antibody (Monoclonal, 33/2)
Boster Bio Anti-Cathepsin L Ctsl Antibody (Monoclonal, 33/2) catalog # MA1014. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Cathepsin L Ctsl Antibody (Monoclonal, 33/2) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1014)
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Procathepsin L isolated from the human lung cancer cell line EPLC 32M1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
No cross-reactivity with other proteins
MA1014 is reactive to Ctsl in Human, Mouse, Rat
MA1014 is guaranteed for IHC, WB Boster Guarantee
Background of Cathepsin L
Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.
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Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.
Immunohistochemistry (Frozen Section), 4μg/ml, Human, mouse, rat, -
Western blot, 2μg/ml, Human, mouse, rat
Validation Images & Assay Conditions
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Boster Kit Box
Gene/Protein Information For Ctsl (Source: Uniprot.org, NCBI)
peptidase C1 family
Cathepsin L; cathepsin L1; CATL; CTSL; CTSL1; CTSLEC 184.108.40.206; EC 3.4.22; FLJ31037; Major excreted protein; MEP Ctsl|CATHL, CatL1, Ctsl|cathepsin L|procathepsin L|CP-2|MEP|cathepsin L1|cyclic protein 2|major excreted protein*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".
For more info on Ctsl, check out the Ctsl Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Ctsl: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected]
No publications found for MA1014
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