Anti-CCDC98 ABRAXAS1 Antibody

Abraxas antibody

Boster Bio Anti-CCDC98 ABRAXAS1 Antibody (Catalog # A32338). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A32338
Size: 0.1 mg
Reactive Species: Human, Mouse
Host: Rabbit
Application: ELISA, IHC-P, WB

Product Name

Anti-CCDC98 ABRAXAS1 Antibody

View all Abraxas Antibodies

SKU/Catalog Number

A32338

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-CCDC98 ABRAXAS1 Antibody (Catalog # A32338). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse.

Storage & Handling

CCDC98 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-CCDC98 ABRAXAS1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A32338)

Host

Rabbit

Contents

CCDC98 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

CCDC98 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human CCDC98. The immunogen is located within amino acids 80 - 130 of CCDC98.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A32338 is reactive to ABRAXAS1 in Human, Mouse

Applications

A32338 is guaranteed for ELISA, IHC-P, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

46.663kDa

Background of Abraxas

CCDC98, also known as Abraxas 1, was identified through protein binding studies using the breast and ovarian predisposition protein BRCA1 as the binding target. CCDC98 recruits RAP80, a ubiquitin-binding protein, to BRCA1, allowing the formation of BRCA1 foci in response to DNA damage caused by ionizing radiation. Both CCDC98 and RAP80 are required for DNA damage resistance, G2-M checkpoint control, and DNA repair. Cells depleted of either CCDC98 or RAP80 exhibited increased sensitivity to ionizing radiation, although not as much as in BRCA1-depleted cells, suggesting that CCDC98 and RAP80 control only part of the DNA damage response role of BRCA1. At least two isoforms of CCDC98 are known to exist.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

CCDC98 antibody can be used for detection of CCDC98 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For ABRAXAS1 (Source: Uniprot.org, NCBI)

Gene Name

ABRAXAS1

Full Name

BRCA1-A complex subunit Abraxas 1

Weight

46.663kDa

Superfamily

FAM175 family

Alternative Names

BRCA1-A complex subunit Abraxas; ABRA1; CCDC98; family with sequence similarity 175, member A ABRAXAS1 ABRA1, CCDC98, FAM175A abraxas 1, BRCA1 A complex subunit BRCA1-A complex subunit Abraxas 1|abraxas protein|coiled-coil domain containing 98|family with sequence similarity 175 member A

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ABRAXAS1, check out the ABRAXAS1 Infographic

ABRAXAS1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ABRAXAS1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Size

Total: $449

SKU:A32338

Backordered.

Lead time for this item is typically 4-7 days

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A32338
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$449.00

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