Anti-CCR2/CKR2 Rabbit Monoclonal Antibody

Product Name

Anti-CCR2/CKR2 Rabbit Monoclonal Antibody

View all Ccr2 Antibodies

SKU/Catalog Number

M00158

Size

100 μl

Form

Liquid

Description

Boster Bio Anti-CCR2/CKR2 Rabbit Monoclonal Antibody catalog # M00158. Tested in WB, IHC, Flow Cytometry, IP applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CCR2/CKR2 Rabbit Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00158)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

AOF-3

Isotype

Rabbit IgG

Immunogen

A synthesized peptide derived from human CCR2/CKR2 Receptor.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00158 is reactive to Ccr2 in Human, Mouse

Applications

M00158 is guaranteed for Flow Cytometry, IP, IHC, WB Boster Guarantee

Observed Molecular Weight

78 kDa

Calculated molecular weight

42.783kDa

Background of Ccr2

Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns (4,5) P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3) . PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Innovating Scientists Reward

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:1000
IHC 1:50-1:200
IP 1:50
FC 1:100

Validation Images & Assay Conditions

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All lanes use the Antibody at 1:500 dilution for 1 hour at room temperature.

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Immunofluorescent analysis using the Antibody at 1:50 dilution.

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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

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Immunohistochemical analysis of paraffin-embedded human tonsil, using CCR2/CKR2 Antibody.

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Immunofluorescent analysis using the Antibody at 1:50 dilution.

Gene/Protein Information For Ccr2 (Source: Uniprot.org, NCBI)

Alternative Names

C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CC-CKR-2CKR2B; CCR2; CCR-2; CCR2A; CCR2B; CD192 antigen; CD192; chemokine (C-C motif) receptor 2; CKR2; CKR2A; CMKBR2; CMKBR2MGC111760; FLJ78302; MCP-1 receptor; MCP-1-R; MCP-1-RMGC103828; MGC168006; Monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor Ccr2|CC-CKR-, CCR, CKR, Cc-ckr-2a, Ccr2b, Ckr2, Ckr2a, Ckr2b, Cmkbr, Cmkbr2, mJe-r, Ccr2|chemokine (C-C motif) receptor 2|C-C chemokine receptor type 2|C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR)|C-C CKR-2|CCR-2|JE/FIC receptor|MCP-1 receptor|MIP-1 alphaR|chemoattractant protein-1 receptor|chemokine (C-C) receptor 2

For more info on Ccr2, check out the Ccr2 Infographic

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In this infographic, you will see the following information for Ccr2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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